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Impact of cannabidiol on viability of normal and tumorigenic human kidney cells...

Sousa, D.; Amaro, F.; Araújo, A. M.; Carvalho, M.

Background: Cannabidiol (CBD), the main non-psychotropic cannabinoid of Cannabis sativa, has several pharmacological actions with therapeutic potential, including antitumor effects [1]; however, its effect on renal cell carcinoma (RCC) is unknown. Considering that recent research suggests that cell culture conditions, particularly the presence of serum in culture medium, may modulate the cannabinoids' antitumor...

Date: 2023   |   Origin: Scientific Letters

Toxicity of amphetamine-type drugs in rat cardiomyocyte cells involves oxidativ...

Valente, M. J.; Araújo, A. M.; Carvalho, F.; Carvalho, M.

Background: Synthetic cathinones (SCs) are recreational psychoactive substances with pharmacological properties resembling those of classical amphetamines, such as 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) [1]. Although the use of SCs has been linked to adverse health outcomes, including myocardial infarction and sudden cardiac deaths [2], the underlying cardiotoxic mechanisms are still unknown. Objecti...

Date: 2023   |   Origin: Scientific Letters

Airway approach for caesarean section under general anaesthesia: a national survey

Pombo, A.; Cardoso, T. M.; Araújo, A. M.; Frada, R.; Nunes, Catarina S.; Órfão, J.; Lemos, P.


Gender differences in first-year College students’ academic expectations

Diniz, A. M.; Alfonso, S.; Araújo, A. M.; Deaño, M.; Costa, A. R.; Conde, Á; Almeida, L. S.

Based on a multidimensional definition of academic expectations (AEs), the authors examine students’ AE component scores across countries and genders. Two samples (343 Portuguese and 358 Spanish students) completed the Academic Perceptions Questionnaire (APQ) six months after enrolling in their universities. Factorial invariance was ensured across countries and genders, allowing us to study AEs using the APQ fo...


Living-donor kidney transplantation: predictive factors and impact on post-tran...

Araújo, A. M.; Santos, F.; Guimarães, J.; Nunes, Catarina S.; Casal, M.

Renal transplantation from living donors represents a valuable opportunity for patients with end-stage renal disease due to short- and long-term outcomes. Nevertheless, it requires that a detailed set of conditions be considered for donor and recipient selection, with possible implications arising from these criteria in the post-transplant outcome. The present work aims to study demographic and clinical charact...


Deceased-donor kidney transplantation: predictive factors and impact on postope...

Santos, F.; Guimarães, J.; Araújo, A. M.; Nunes, Catarina S.; Casal, M.

Kidney transplantation (KT) is the treatment of choice in end stage renal disease. Patients proposed for KT have multiple comorbidities, which makes KT a challenge. Our aim was to assess predictive factors for postoperative complications in deceased-donor KT. For data statistical analysis, logistic and linear regressions were used. Between 2012 and 2013, 113 KTs were performed in patients with a mean age 49.9 y...


Living-donor and deceased-donor renal transplantation: differences in early out...

Guimarães, J.; Araújo, A. M.; Santos, F.; Nunes, Catarina S.; Casal, M.

Living-donor renal transplant (LDRT) yields better long-term outcomes than cadaver-donor renal transplant (CDRT). The aim of the present study was to identify the differences in the early postoperative period between LDRT and CDRT recipients. A retrospective study was conducted including all patients receiving a LDRT and CDRT in this center in 2012 and 2013. A total of 153 recipients were identified (CDRT n = 1...


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