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Recurrent Appendicitis in Children: The Impact of a Poorly Known Disease

Monteiro, S; Capela, M; Araújo, AR; Tavares, M; Pinto, J

Chronic and recurrent appendicitis is rare in pediatric patients and can be easily misdiagnosed due to its unusual presentation and low incidence rate. We present the case of an 11-year-old male with recurrent right lower quadrant (RLQ) pain persisting for 19 months. The patient experienced pain flare-ups accompanied by paleness and gait limp, without fever or other symptoms. Despite extensive medical examinati...


Novel Ocellatin Peptides Mitigate LPS-induced ROS Formation and NF-kB Activatio...

Sousa, NA; Oliveira, GAL; Oliveira, AP; Lopes, ALF; Iles, B; Nogueira, KM; Araújo, TSL; Souza, LKM; Araújo, AR; Ramos-Jesus, J; Plácido, A; Amaral, C

Cutaneous secretions of amphibians have bioactive compounds, such as peptides, with potential for biotechnological applications. Therefore, this study aimed to determine the primary structure and investigate peptides obtained from the cutaneous secretions of the amphibian, Leptodactylus vastus, as a source of bioactive molecules. The peptides obtained possessed the amino acid sequences, GVVDILKGAAKDLAGH and GVV...


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