153 documents found, page 1 of 16

O cuidado ao doente em morte iminente nas enfermarias de medicina interna em Po...

Contexto: Em Portugal, dois terços das mortes ocorrem no hospital. Não há dados nacionais que caracterizem a forma como os doentes em morte iminente (Mi) últimas horas ou dias de vida internados nos serviços de Medicina Interna (MI) portugueses são cuidados. Objetivos: Caracterizar (1) o cuidado de doentes em Mi em enfermarias de MI nacionais, segundo os elementos de boas práticas previamente validados; (2) a p...

Descriptive analysis of PD-L1 expression in non-small cell lung carcinoma biops...

Introduction: The expression of PD-L1 as a predictive marker of response to treatment of non-small cell lung cancer (NSCLC) allows the identification of patients most likely to benefit from treatment with inhibitors of immune checkpoints. The main objective of this study was to determine the PD-L1 positivity/negativity rates of biopsies diagnosed with NSCLC during the year 2017 and 2018 at CHUPorto and compare ...

A novel shortcut to cubical perspective drawing

The article introduces a novel construction that simplifies the drawing of cubical perspectives. A recent work described a method for drawing cubical perspectives which classifies lines into several types and renders each type systematically. Some of these types require an auxiliary external construction, hindering the drawing process. This research proposes a novel method that shortcuts this step with an inter...

Prospective workflows for generative AI-assisted immersive illustration: the ca...

The introduction of generative AI into the field of immersive illustration threatens to displace both the knowledge of perspective and the practice of drawing as the main tools of this very technical branch of illustration. Yet for many illustrators this type of technical drawing is not just a tool but an end in itself. We consider what future workflows may accommodate both AI and handmade drawing in a way comp...

Stream sediment pollution: a compositional baseline assessment

A high concentration of potentially toxic elements (PTEs) can affect ecosystem health in many ways. It is therefore essential that spatial trends in pollutants are assessed and monitored. Two questions must be addressed when quantifying pollution: how to define a non-polluted sample and how to reduce the problem’s dimensionality. A geochemical dataset is a composition of variables (chemical elements), where the...

Fatal Case of Immune-Related Myocarditis and Myositis Due to Treatment with Imm...

Immune checkpoint inhibitor and tyrosine kinase inhibitor combinations have become the new standard of care in the first-line treatment of metastatic clear cell renal cell carcinoma. However, there is a growing concern regarding severe immune-related adverse events. A 78-year-old man with metastatic clear cell renal cell carcinoma, treated with pembrolizumab and axitinib, was admitted to the emergency departmen...

Lung Cancer Screening in Portugal: A PULMONALE Pilot Project

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Prognostic value of neutrophil/lymphocyte racio in palliative non-small cell lu...

Introduction: Immune checkpoint inhibitors (IC) are a new therapeutic option for non-small cell lung cancer. A higher neutrophil/lymphocyte ratio has been associated with worse outcomes in patients treated with immune checkpoint inhibitors, lung cancer included. Aim: Study the relation between value of neutrophil/lymphocyte ratio at day one (D1) and day 30 (D30) of treatment, and overall survival (OS) and progr...

Stream sediment pollution: a compositional baseline assessment

A high concentration of potentially toxic elements (PTEs) can affect ecosystem health in many ways. It is therefore essential that spatial trends in pollutants are assessed and monitored. Two questions must be addressed when quantifying pollution: how to define a non-polluted sample and how to reduce the problem’s dimensionality. A geochemical dataset is a composition of variables (chemical elements), where the...

Emílio Rui Vilar - memórias de dois regimes