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Carvacrol, (−)-borneol and citral reduce convulsant activity in rodents

Quintans-Júnior, Lucindo José; Guimarães, Adriana Gibara; Araújo, Bruno Eduardo Silva de; Cavalcanti, Sócrates Cabral de Holanda

Carvacrol, a monoterpenic phenol present in essential oils of the Labiatae family, has been used through the ages as a source of flavor in food and for medicinal purposes. Borneol is a monoterpene found in several species of Artemisia and Dipterocarpaceae, used for anxiety, pain and anesthesia in traditional Chinese. Citral, a mixture of two geometrical isomers (neral and geranial), is one of the most important...

Date: 2013   |   Origin: Oasisbr

Citral reduces nociceptive and inflammatory response in rodents

Quintans-Júnior, Lucindo José; Guimarães, Adriana Gibara; Santana, Marília Trindade de; Araújo, Bruno Eduardo Silva de; Moreira, Flávia Viana

Citral (CIT), which contains the chiral enantiomers, neral (cis) and geranial (trans), is the majority monoterpene from Lippia alba and Cymbopogon citratus. The present study aimed to evaluate CIT for antinociceptive and anti-inflammatory activities in rodents. Antinociceptive and anti-inflammatory effects were studied by measuring nociception through acetic acid and formalin tests, while inflammation was verif...

Date: 2013   |   Origin: Oasisbr

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