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PROBLEM-SOLVING METHODOLOGY - THE ILUSTRE CASA DE RAMIRES PROJECT PROPOSAL

Marques Dos Santos, Paula; Araújo, Carlos; Barrosa, Paulo; Dias, Xavier

constant vicissitudes arising from competition, economic and social crises and the need to develop solutions based on efficiency and sustainability, require the professionals of the future to have a critical thinking capacity and skills that enable them to use the abstract scientific and technical knowledge they have acquired to solve concrete situations and problems. These are the skills that organizations exp...


Cirrhosis is associated with lower serological responses to COVID-19 vaccines i...

Simão, André; Palma, Carolina; Izquierdo-Sanchez, Laura; Putignano, Antonella; Carvalho-Gomes, Angela; Posch, Andreas; Zanaga, Paola; Girleanu, Irina

Background & aims: The response of patients with chronic liver disease (CLD) to COVID-19 vaccines remains unclear. Our aim was to assess the humoral immune response and efficacy of two-dose COVID-19 vaccines among patients with CLD of different aetiologies and disease stages. Methods: A total of 357 patients were recruited in clinical centres from six European countries, and 132 healthy volunteers served as con...


Health Problems During and After Travel: A Prospective Observational Study in a...

Conceição, Cláudia; Medeiros, Márcia; Pereira, Nélia; Gonçalves, Luzia; Antunes, Abilio; Blondé, Ellen; Teodósio, Rosa; Araújo, Carlos

Introduction: In order to improve the health of travellers during travel it is important to better understand the health problems faced by travellers in different destinations. The main objective of this study was to characterise the perceived health problems of travellers during and up to six months after travel on a pre-travel clinic in Lisbon, Portugal.Material and Methods: This is a prospective observationa...

Date: 2021   |   Origin: Acta Médica Portuguesa

Preliminary evaluation of WRF physical parameterizations for a frost event in S...

Machado, Jeferson [UNESP]; Quadro, Mário; Cardoso, Camila; Araújo, Carlos; Rodrigues, Gabriel; Costa, Natália; Rodrigues, Tuanny; de Paula, Lourenço

Made available in DSpace on 2019-10-06T16:08:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-07-01; Based on numerical simulations performed with the WRF model for a frost event in Southern Brazil in July 2013, it was possible to test different physical parameterizations and evaluate these parameterizations in these weather conditions. Although the results do not show considerable statistical differen...

Date: 2019   |   Origin: Oasisbr

Travel medicine in Portugal: workshop and launch of the portuguese society of t...

Conceição, Cláudia; Teodósio, Rosa; Pereira, Filomena; Racha Pacheco, Ricardo; Araújo, Carlos; Seixas, Jorge; Atouguia, Jorge

Travel Medicine, as we know it today, started in Portugal during the late 1990’s. The recent wave of Portuguese citizens migrating to tropical countries gave a new impulse to this discipline. This Workshop on Travel Medicine was an excellent opportunity to invite representatives of Portuguese travel medicine clinics to discuss the problems of this practice, and the right moment to launch the Portuguese Society ...


Identification of two new candidate genes OAF and PVRL1 for Peters anomaly and ...

David, Dezső; Anand, Deepti; Araújo, Carlos; Gloss, Brian; Fino, Joana; Marques, Bárbara; Dinger, Marcel; Lindahl, Päivi; Pöyhönen, Minna


Co-segregation of trichorhinophalangeal syndrome with a t(8;13)(q23.3;q21.31) f...

David, Dezső; Marques, Bárbara; Ferreira, Cristina; Araújo, Carlos; Vieira, Luís; Soares, Gabriela; Dias, Cristina; Pinto, Maximina

Trichorhinophalangeal syndrome type I (TRPS I) is a rare autosomal dominant syndrome caused by haploinsufficiency of TRPS1 due to point mutations or deletions. Here we report the first familial TRPS I due to a t(8;13)(q23.3;q21.31) translocation breakpoint <100 kb from the 5’ end of TRPS1. Based on the additional abnormalities observed exclusively in the index patient that are mainly compatible with clinical fe...


Tricho-rhino-phalangeal syndrome type I as a “cis-ruption disorder” caused by a...

Marques, Bárbara; Ferreira, Cristina; Araújo, Carlos; Vieira, Luís; Martins, Márcia; Pinto, Maximina; Dias, Cristina; David, Dezső

Tricho-rhino-phalangeal syndrome type I (TRPS I; OMIM 190350) and type II (OMIM 150230) are two forms of the rare autosomal-dominant TRP malformation syndrome localised in 8q23.3–24.1. TRPS I is generally caused by point mutations or deletions of the TRPS1 gene, whereas type II is characterised by the presence of multiple cartilage exostoses (EXT) and deletions comprising the TRPS1 and EXT1 genes. In the presen...


Cerebral and spinal cord toxoplasmosis: a clinical case report

San Martin, Francisco Javier; Baptista, Teresa; Araújo, Carlos

The authors describe a case of cerebral and spinal cord Toxoplasmosis as the first manifestation of AIDS, in a patient who’s HIV infection was unknown.In this context, opportunistic infections usually appear, when the number of TCD4 lymphocytes are under 200 cells/μL.Toxoplasmosis is the most frequent cause of focal cerebral injuries in patients infected with HIV; however, Spinal cord injury due to Toxoplasma g...


Polyradiculopathy in an AIDS patient with CMV infection

Augusto, Vítor; Leal, Alberto; Araújo, Carlos; Champalimaud, J. Luís

The authors report a case of an HIV1 seropositive homosexual male who develops an axonal progres­sive and ascendent subacute polyradiculoneuropha­ty, polymorphonuclear pleocytosis compatibly asso­ciated whit clinical diagnostic of cytomegalovirus nervous system infection. This entity is rare, and is of di.fficult laboratorial confirmation and resistant to terapheutical measures as reported in literature.; Os au...


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