58 documents found, page 1 of 6
NADES-in-Oil Emulsions Enriched with Essential Oils for Cosmetic Application
Freitas, David; Rocha, Diana; Santos, Joana; Noro, Jennifer Martins; Tavares, Tânia D.; Teixeira, Marta O.; Araújo, Daniela; Castro, Joana Isabel ReisThis research aims to explore the potential benefits of natural deep eutectic solvents (NADES) in formulating translucent NADES-in-oil emulsions (TEs) containing essential oils (EOs) for cosmetic applications. The TEs investigated in this study are based on previous formulations, consisting of 50 wt.% egg phosphatidylcholine (EPC), 20 wt.% ethanol, 20 wt.% olive oil (OlO), thyme oil (TO), or oregano oil (OrO), ...
Advances in whole genome sequencing for foodborne pathogens: implications for c...
Gomes, Emílio; Araújo, Daniela; Nogueira, Teresa; Oliveira, Ricardo; Silva, Sónia Carina; Oliveira, Lorena V. N.; Azevedo, Nuno F.; Almeida, CarinaFoodborne outbreaks affecting millions of people worldwide are a significant and growing global health threat, exacerbated by the emergence of new and increasingly virulent foodborne pathogens. Traditional methods of detecting these outbreaks, including culture-based techniques, serotyping and molecular methods such as real-time PCR, are still widely used. However, these approaches often lack the precision and ...
Swine industry: validated PCR-based method for detecting enterotoxigenic Escher...
Barros, Margarida; Castro, Joana Isabel Reis; Oliveira, Ricardo; Campos, Ana Maria; Araújo, Daniela; Silva, Sónia Carina; Almeida, Gonçalo Nieto[Excerpt] Enterotoxigenic E. coli (ETEC) infections lead to significant costs for the swine industry worldwide. Bacterial fimbriae (F4/F5/F6/F18/F41) allow the adhesion of the bacteria to epithelial cells, and when both the immunological systems and the gut mic ro biota are poorly developed, ETEC colonizes and produces one or more enterotoxins (LT/ STa/ STb) that can have local and systemic effects. Therefore, ...
Assessing host-adaptation of new sequence types of livestock-associated methici...
Oliveira, Ricardo; Araújo, Daniela; Castro, Joana Isabel Reis; Nogueira, Teresa; Almeida, Gonçalo; Azevedo, Nuno F.; Almeida, CarinaThe importance of animals as reservoirs of human pathogens is widely recognised, with livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) being consistently reported. This study presents a phenotypic and genotypic characterization of five MRSA isolates from raw bovine milk in northern Portugal, using culturomics and whole genome sequencing (WGS), to assess their potential risk for human i...
Students' summer internships in a research centre: the impact on scientific lit...
Saraiva, Elisa; Silva, Sónia Carina; Castro, Joana Isabel Reis; Araújo, Daniela; Almeida, Carina Manuela Fernandes; Azevedo, Maria ManuelScience communication is crucial for engaging society in real-life contexts. In this line of thought, research centres play a pivotal role in promoting dynamic and interactive communication that enables science to be disseminated. This study constitutes a qualitative research based on a case study involving middle school students, researchers and teachers, which took place in a research centre in Portugal that ...
Application of antisense therapy to control Nakaseomyces glabratus infections
Serra, Patrícia; Gonçalves, Bruna; Henriques, Mariana; Castro, Joana; Araújo, Daniela; Silva, Sónia CarinaCanclicla infections affect billions of people worlclwicle, with high morbidity ancl mortality rates (40-60CX,) [l] ancl require long hospital stays ancl increase healthcare costs, which places a significant socio-economic burclen on the economy [2]. Canclicla glabrata (now reclassified as Nakaseomyces glabratus) poses a significant clinical challenge, clue to its increasing levels of resistance to conventional...
Comprehensive molecular characterization of anti-EFG1 2'OMe effects on C. albic...
Silva, Diana; Silva, Sónia Carina; Henriques, Mariana; Araújo, Daniela; Gonçalves, Bruna FernandesCandidiasis is a fungal infection primarily caused by Candida albicans. It affects millions of people worldwide and poses significant clinical challenges, resulting in high morbidity and mortality rates, largely due to increasing resistance to conventional antifungal therapies resulting from their widespread use [1]. Innovative therapies, such as antisense oligonucleotides (ASOs), are being explored to address ...
Advances in whole genome sequencing for foodborne pathogens: implications for c...
Gomes, Emílio; Araújo, Daniela; Nogueira, Teresa; Oliveira, Ricardo; Silva, Sónia; Oliveira, Lorena V. N.; Azevedo, Nuno F.; Almeida, CarinaFoodborne outbreaks affecting millions of people worldwide are a significant and growing global health threat, exacerbated by the emergence of new and increasingly virulent foodborne pathogens. Traditional methods of detecting these outbreaks, including culture-based techniques, serotyping and molecular methods such as real time PCR, are still widely used. However, these approaches often lack the precision andr...
Evaluation of antibacterial properties of Lactobacillus acidophilus and Lactoba...
Araújo, Daniela; Silva, A. R.; Silva, Sónia Carina; Mira, N. P.; Almeida, Carina; Castro, Joana Isabel ReisPost-weaning diarrhea (PWD) in piglets, caused by enterotoxigenic Escherichia coli (ETEC), has been managed using antibiotics and zinc oxide. However, concerns regarding antibiotic resistance as well as the 2022 EU ban on zinc oxide, have prompted the development of sustainable alternatives. Growing evidence suggests that probiotics may play a promising role in controlling ETEC infections. In this study, we fir...
In vitro investigation of the antimicrobial properties of Gerês propolis in bac...
Rodrigues, Rafael; Almeida, Rui; Rodrigues, Soraia C. V.; Castro, Joana Isabel Reis; Oliveira, Ricardo; Mendes, Nuno; Almeida, CarinaPropolis, also known as bee glue, is a natural resinous mixture produced by Western honeybees and has long been recognized for its potential therapeutic properties. Recent research has focused on its diverse bioactivities, particularly its antimicrobial effects against a broad spectrum of microorganisms, including human but also animal pathogens. However, further investigation is required to fully elucidate the...