3 documents found, page 1 of 1
Resistance profile of osimertinib in pre-treated patients with EGFR T790M-mutat...
Fernandes, Maria Gabriela O.; Sousa, Catarina; Jacob, Maria; Almeida, Leonor; Santos, Vanessa; Araújo, David; Bastos, Hélder Novais; Magalhães, AdrianaOsimertinib efficacy in pre-treated patients with epidermal growth factor receptor (EGFR) T790M-mutated non-small cell lung cancer (NSCLC) has been demonstrated in clinical trials, but real-world data, particularly regarding resistance profile, remains limited. This study aims to analyze the resistance mechanisms acquired after treatment with Osimertinib. Clinical outcomes and molecular results from re-biopsie...
Morphological and physiological responses of strawberry to a biostimulant and c...
Wang, Maling; Araújo, David; Vasconcelos, Marta; Gomes, M. Helena; Carvalho, Susana M.P.
A prediction rule to stratify mortality risk of patients with pulmonary tubercu...
Bastos, Hélder Novais; Osório, Nuno S.; Castro, António G.; Ramos, Angélica; Carvalho, Teresa; Meira, Leonor; Araújo, David; Almeida, LeonorTuberculosis imposes high human and economic tolls, including in Europe. This study was conducted to develop a severity assessment tool for stratifying mortality risk in pulmonary tuberculosis (PTB) patients. A derivation cohort of 681 PTB cases was retrospectively reviewed to generate a model based on multiple logistic regression analysis of prognostic variables with 6-month mortality as the outcome measure. A...