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Novel Antiretroviral Therapeutic Strategies for HIV.

Cunha, Rita F.; Simões, Sandra; Carvalheiro, Manuela; Azevedo-Pereira, José Miguel; Santos-Costa, Quirina; Ascenso, Andreia

When the first cases of HIV infection appeared in the 1980s, AIDS was a deadly disease without any therapeutic alternatives. Currently, there is still no cure for most cases mainly due to the multiple tissues that act as a reservoir for this virus besides the high viral mutagenesis that leads to an antiretroviral drug resistance. Throughout the years, multiple drugs with specific mechanisms of action on distinc...


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