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Effects of passive inhalation of cigarette smoke on structural and functional p...

Vasconcelos, Thiago Brasileiro de; Araújo, Fernanda Yvelize Ramos de; Pinho, João Paulo Melo de; Soares, Pedro Marcos Gomes

Objective: To evaluate the effects of passive inhalation of cigarette smoke on the respiratory system of guinea pigs. Methods: Male guinea pigs were divided into two groups: control and passive smoking, the latter being exposed to the smoke of ten cigarettes for 20 min in the morning, afternoon and evening (30 cigarettes/day) for five days. After that period, inflammatory parameters were studied by quantifying ...

Date: 2016   |   Origin: Oasisbr

Estudo do efeito antipsicótico do óleo essencial de Alpinia zerumbet em compara...

Araújo, Fernanda Yvelize Ramos de

Schizophrenia is a chronic psychiatric disorder characterized by the presence of positive, negative and cognitive symptoms. A widely used animal model involves repeated administration of ketamine (TEC) that induces the disease symptoms as well as causes oxidative damage. The Alpinia zerumbet is a plant whose essential oil (OEAZ) has shown important antipsychotic effect in previous studies of our research group....

Date: 2016   |   Origin: Oasisbr

Time course of the effects of lipopolysaccharide on prepulse inhibition and bra...

Custódio, Charllyany Sabino; Mello, Bruna Stefânia Ferreira; Cordeiro, Rafaela Carneiro; Araújo, Fernanda Yvelize Ramos de; Chaves, João Henrique

The systemic administration of lipopolysaccharide (LPS) induces time-dependent behavioral alterations, which are related to sickness behavior and depression. The time-course effects of LPS on prepulse inhibition (PPI) remain unknown. Furthermore, the time-dependent effects of LPS on central nitrite content had not been investigated. Therefore, we studied alterations induced by single LPS (0.5 mg/kg, i.p.) admin...

Date: 2014   |   Origin: Oasisbr

Avaliação dos possíveis efeitos antipsicóticos da Alpinia zerumbet em camundongo

Araújo, Fernanda Yvelize Ramos de

Alpinia zerumbet (Pers.), zingiberaceae family, is a species known in Brazil as a colony. The essential oil of Alpinia zerumbet (OEAZ) extracted from leaves of the plant has been evaluated in classic animal models of drug screning with activity in anxiety, depression, seizures, psychosis and antioxidant, such as the open field, rota rod, tail suspension, forced swimming, plus-maze, seizures induced by electrosh...

Date: 2012   |   Origin: Oasisbr

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