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A single dose of COVID-19 vaccine induces a strong T cell and B cell response i...

Laranjeira, Paula; Rodrigues, Tiago; Silva, Ana; Barbosa, Pedro; Reis, Teresa; Lopes, Cristiana; Pinho, Aryane; Silva, Sandra; Silva, Isabel

A broad understanding on how SARS-CoV-2 infection and vaccination mobilize the immune system is necessary to find the best predictors of long-term protection and identify individuals that would benefit from additional vaccine doses. This study aims to understand the effect of a single dose of Pfizer-BioNTech BNT162b2 COVID-19 vaccine, in individuals recovered from SARS-CoV-2 infection, on circulating CD4+ T fol...


COVID-19 vaccine effectiveness among healthcare workers: a hospital-based cohor...

Gaio, Vânia; Santos, Ana João; Amaral, Palmira; Faro Viana, João; Antunes, Isabel; Pacheco, Vânia; Paiva, Artur; Pinto Leite, Pedro

Objectives Healthcare workers (HCWs) were the first to be prioritised for COVID-19 vaccination. This study aims to estimate the COVID-19 vaccine effectiveness (VE) against SARS-CoV- 2 symptomatic infection among HCWs in Portuguese hospitals. Design Prospective cohort study. Setting and participants We analysed data from HCWs (all professional categories) from three central hospitals: one in the Lisbon and Tagus...


COVID-19 vaccine effectiveness among healthcare workers: a hospital-based cohor...

Gaio, Vânia; Santos, Ana João; Amaral, Palmira; Faro Viana, João; Antunes, Isabel; Pacheco, Vânia; Paiva, Artur; Pinto Leite, Pedro

Objectives: Healthcare workers (HCWs) were the first to be prioritised for COVID-19 vaccination. This study aims to estimate the COVID-19 vaccine effectiveness (VE) against SARS-CoV-2 symptomatic infection among HCWs in Portuguese hospitals. Design: Prospective cohort study. Setting and participants: We analysed data from HCWs (all professional categories) from three central hospitals: one in the Lisbon and Tag...


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