12 documents found, page 1 of 2
Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features...
Resende, Lucilene Aparecida; Soares, Rodrigo Dian de Oliveira Aguiar; Ker, Henrique Gama; Roatt, Bruno Mendes; Mendonça, Ludmila Zanandreis deFundação de Amparo a Pesquisa do Estado de Minas Gerais. Belo Horizonte, MG, Brazil; Universidade Federal de Minas Gerais. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brazil/Universidade Federal de Ouro Preto. Instituto de Ciências Exatas e Biológicas. Núcleo de Pesquisas em Ciências Biológicas/NUPEB Laboratório de Imunopatologia. Ouro Preto, MG, Brazil; Uni...
Experimental benznidazole treatment of Trypanosoma cruzi II strains isolated fr...
Silva, Jaquelline Carla Valamiel de Oliveira e; Assis, Girley Francisco Machado de; Oliveira, Maykon Tavares de; Paiva, Nívia Carolina Nogueira deTrypanosoma cruzi strains from distinct geographic areas show differences in drug resistance and association between parasites genetic and treatment response has been observed. Considering that benznidazole (BZ) can reduce the parasite burden and tissues damage, even in not cured animals and individuals, the goal is to assess the drug response to BZ of T. cruzi II strains isolated from children of the Jequitinh...
Analysis using canine peripheral blood for establishing in vitro conditions for...
Viana, Kelvinson Fernandes; Soares, Rodrigo Dian de Oliveira Aguiar; Roatt, Bruno Mendes; Resende, Lucilene Aparecida; Lemos, Denise da SilveiraCanine visceral leishmaniasis (CVL) is a parasitic disease endemic in many countries, anddogs present as the major natural reservoir of the parasite, Leishmania chagasi (syn. L.infantum). Biomarkers in the canine immune system is an important technique in thecourse of developing vaccines and treatment strategies against CVL. New methodologiesfor studying the immune response of dogs during Leishmania infection a...
Immunophenotypic features of tumor infiltrating lymphocytes from mammary carcin...
Lima, Alessandra Estrela da Silva; Araújo, Márcio Sobreira Silva; Costa Neto, João Moreira da; Carvalho, Andréa Teixeira; Melo, Stella Maria BarrouinSubmitted by Alessandra Estrela-Lima (aestrela@ufba.br) on 2012-02-08T13:22:32Z No. of bitstreams: 1 1471-2407-10-256.pdf: 1289024 bytes, checksum: 9cd94ffd31f2b125198c19ed8f3350c7 (MD5); Made available in DSpace on 2012-02-08T13:22:32Z (GMT). No. of bitstreams: 1 1471-2407-10-256.pdf: 1289024 bytes, checksum: 9cd94ffd31f2b125198c19ed8f3350c7 (MD5) Previous issue date: 2010-06; Background: The immune system pla...
Understanding of the immunological heterogeneity of canine mammary carcinomas t...
Lima, Alessandra Estrela da Silva; Araújo, Márcio Sobreira Silva; Costa Neto, João Moreira da; Ribeiro, Lorena; Damasceno, Karine AraújoAcesso restrito: texto completo. p. 751-763; Submitted by Alessandra Estrela-Lima (aestrela@ufba.br) on 2012-02-10T17:46:05Z No. of bitstreams: 1 estrela lima 2011.pdf: 705375 bytes, checksum: f2952082dfbef55fa5c9f46053e963c7 (MD5); Made available in DSpace on 2012-02-10T17:46:05Z (GMT). No. of bitstreams: 1 estrela lima 2011.pdf: 705375 bytes, checksum: f2952082dfbef55fa5c9f46053e963c7 (MD5) Previous issue dat...
Immunophenotypic features of tumor infiltrating lymphocytes from mammary carcin...
Lima, Alessandra Estrela da Silva; Araújo, Márcio Sobreira Silva; Costa Neto, João Moreira da; Carvalho, Andréa Teixeira; Melo, Stella Maria BarrouinSubmitted by Alessandra Estrela-Lima (aestrela@ufba.br) on 2012-02-10T18:57:32Z No. of bitstreams: 1 Estrela-Lima et al. BMC Cancer 2010.pdf: 1289024 bytes, checksum: 9cd94ffd31f2b125198c19ed8f3350c7 (MD5); Made available in DSpace on 2012-02-10T18:57:32Z (GMT). No. of bitstreams: 1 Estrela-Lima et al. BMC Cancer 2010.pdf: 1289024 bytes, checksum: 9cd94ffd31f2b125198c19ed8f3350c7 (MD5) Previous issue date: 2010...
Immunological changes in canine peripheral blood leukocytes triggered by immuni...
Araújo, Márcio Sobreira Silva; Andrade, Renata Aline de; Avelar, Renato Sathler; Magalhães, Camila Paula; Carvalho, Andréa Teixeira deIn this study, we summarized the major phenotypic/functional aspects of circulating leuko-cytes following canine immunization with Leishvaccine and Leishmune ®. Our findings showed that Leishvaccine triggered early changes in the innate immunity (neutrophils and eosinophils) with late alterations on monocytes. Conversely, Leishmune ® induced early phenotypic changes in both, neutrophils and monocytes. Moreover,...
Plasmodium berghei NK65 induces cerebral leukocyte recruitment in vivo : an int...
Queiroz, Norinne Lacerda; Lima, Onésia Cristina Oliveira; Carneiro, Cláudia Martins; Vilela, Márcia de Carvalho; Teixeira, Antônio LúcioMalaria is second only to tuberculosis as the leading cause of morbidity and mortality as a consequence of a single infectious agent. Much of the pathology of malaria arises from the inappropriate or excessive immune response mounted by the host in an attempt to eliminate the parasite. We here report the inflammatory changes observed in the cerebral microvasculature of C57BL/6 and BALB/c mice that had been inoc...
Despite Leishvaccine and Leishmune ® trigger distinct immune profiles, their ab...
Araújo, Márcio Sobreira Silva; Andrade, Renata Aline de; Vianna, Leonardo Rocha; Mayrink, Wilson; Reis, Alexandre Barbosa; Avelar, Renato SathlerPhenotypic features of peripheral blood leukocytes have been investigated as a prerequisite to characterize the protective immunity attributed to both Leishvaccine and Leishmune ® . Our results showed that either those vaccine were accompanied by distinct profiles on innate immune compartment. While Leishvaccine promoted early changes in phenotypic fea-tures of neutrophils and eosinophils with late involvement ...
Trypanosoma cruzi : desferrioxamine decreases mortality and parasitemia in infe...
Arantes, Jerusa Marilda; Francisco, Amanda Fortes; Vieira, Paula Melo de Abreu; Silva, Maísa; Araújo, Márcio Sobreira SilvaDesferrioxamine (DFO) is a potent iron chelator that is also known to modulate inflammation and act as an efficient antioxidant under normal conditions and under oxidative stress. Many in vitro and in vivo studies have shown the efficacy of DFO in the treatment of viral, bacterial and protozoan infections. DFO is known to reduce the intensity of Trypanosoma cruzi infections in mice even during a course of thera...