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Purification of chitosanases produced by Bacillus toyonensis CCT 7899 and funct...

Dantas, Julia Maria de Medeiros; Araújo, Nathália Kelly de; Silva, Nayara Sousa da; Torres-Rêgo, Manoela; Furtado, Allanny Alves

Chitooligosaccharides (COS) have a great potential to be used by pharmaceutical industry due to their many biological activities. The use of enzymes to produce them is very advantageous, however it still faces many challenges, such as discovering new strains capable to produce enzymes that are able to generate bioactive oligosaccharides. In the present study a purification protein protocol was performed to puri...


Anti-ophidian activity of Bredemeyera floribunda Willd. (Polygalaceae) root ext...

Alves, Natacha Teresa Queiroz; Ximenes, Rafael M.; Jorge, Roberta J. B.; Silveira, J. A. M.; Santos, J. V. A.; Rodrigues, F. A. P.; Costa, P. H. S.

Bredemeyera floribunda roots are popularly used to treat snakebites in the semiarid region of Northeast Brazil, and previous studies indicate the anti-ophidian actions of triterpenoid saponins found in its roots. To assess B. floribunda root extract (BFRE) activity against the effects of Bothrops jararacussu venom (BjuV), antiphospholipasic, antiproteolytic, antihemorrhagic, antinecrotic, and anti-edematogenic ...

Date: 2019   |   Origin: Oasisbr

Activity of Fabaceae species extracts against fungi and Leishmania : vatacarpan...

Santana, Dandara Braga; Costa, Raphaella Correia da; Araújo, Renata Mendonça; Paula, José Elias de; Silveira, Edilberto Rocha; Braz-Filho, Raimundo

Leishmaniasis and fungal infection treatment efficacy is limited by toxicity and ever increasing resistance to available drugs, requiring development of alternative compounds. The richness of Cerrado plant antimicrobial secondary metabolites justifies screening of Fabaceae species extracts: Enterolobium ellipticum Benth., Sclerolobium aureum (Tul.) Baill. and Vatairea macrocarpa(Benth.) Ducke, against Leishmani...

Date: 2017   |   Origin: Oasisbr

Antinociceptive effect of the essential oil obtained from the leaves of Croton ...

Nogueira, Lenise de Morais; Silva, Monalisa Ribeiro da; Santos, Simone Maria dos; Albuquerque, Julianna Ferreira Cavalcanti de; Ferraz, Igor Cavalcanti

Croton cordiifolius Baill. is a shrub known as “quebra-faca” and is used to treat inflammation, pain, wounds, and gastrointestinal disturbances in the semiarid region in the northeast of Brazil. In an ethnobotanical survey in the state of Pernambuco, “quebra-faca” use was cited in 33% of the interviews. Thus, we decided to evaluate the antinociceptive effects of the essential oil from C. cordiifolius (CcEO). Ch...

Date: 2016   |   Origin: Oasisbr

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