2 documents found, page 1 of 1
Novel ocellatin peptides mitigate LPS-induced ROS formation and NF-kB activatio...
Sousa, Nayara A.; Oliveira, Guilherme A. L.; de Oliveira, Ana Patrícia; Lopes, André Luís F.; Iles, Bruno; Nogueira, Kerolayne M.; Araújo, Thiago S. L.Cutaneous secretions of amphibians have bioactive compounds, such as peptides, with potential for biotechnological applications. Therefore, this study aimed to determine the primary structure and investigate peptides obtained from the cutaneous secretions of the amphibian, Leptodactylus vastus, as a source of bioactive molecules. The peptides obtained possessed the amino acid sequences, GVVDILKGAAKDLAGH and GVV...
Lactobacillus reuteri DSM 17938 protects agains gastric damage induced by ethan...
Oliveira, Ana P.; Souza, Luan K. M.; Araújo, Thiago S. L.; Araújo, Simone de; Nogueira, Kerolayne M.; Sousa, Francisca Beatriz M.; Silva, Renan O.This study aimed to evaluate the effect of Lactobacillus reuteri DSM 17938 (DSM) on ethanol-induced gastric injury, and if its possible mechanism of action is related to inhibiting the transient receptor potential vanilloid type 1 (TRPV1). We evaluated the effect of supplementing 108 CFU g body wt1 day1 of DSM on ethanol-induced gastric injury. DSM significantly reduced the ulcer area (1.940 1.121 mm2) with 3 d...