3 documents found, page 1 of 1
New Epimeric Spirostanol and Furostanol-Type Steroidal Saponins from Cestrum la...
Ribeiro,Paulo R. V.; Braz-Filho,Raimundo; Araújo,Ana J.; Costa-Lotufo,Letícia V.; Souza,Luciana G. S.; Nobre Junior,Hélio V.; Silva,Cecília R. daFour new epimeric spirostanol and furostanol-type steroidal saponins, (25R,S)-5α-spirostan-2α,3β-diol 3-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranosyl-(1→4)-β-D-galactopyranoside, (25R,S)-5α-spirostan-2α,3β-diol 3-O-β-D-glucopyranosyl-(1→2)-α-L-rhamnopyranosyl-(1→4)-β-D-galactopyranoside, 26-O-β-D-glucopyranosyl-(25R,S)-5α-furost-20-ene,2α,3β-diol 3-O-β-D-galactopyranoside and 26-O-β-D-glucopyranosyl-(25R,S)-5...
New Terpenoids from Croton limae (Euphorbiaceae)
Sousa,Antonio H.; Silva Junior,José N.; Guedes,Maria L. S.; Braz-Filho,Raimundo; Costa-Lotufo,Letícia V.; Araújo,Ana J.; Silveira,Edilberto R.
Cytotoxic, trypanocidal activities and physicochemical parameters of nor-²-lapa...
Silva Júnior,Eufrânio N. da; Moura,Maria Aline B. F. de; Pinto,Antonio V.; Pinto,Maria do Carmo F. R.; Souza,Maria Cecília B. V. de; Araújo,Ana J.The cytotoxicities of five nor-²-lapachone-based 1,2,3-triazoles and the precursor azidonaphthoquinone were assayed against six neoplasic cancer cell lines: SF-295 (central nervous system), HCT-8 (colon), MDAMB-435 (melanoma), HL-60 (leukaemia), PC-3 (prostate) and B-16 (murine melanoma). IC50 values ranging from 0.43 to 9.48 µM were obtained. 3-(4-(1-hydroxycyclohexyl)-1H-1,2,3-triazol-1yl)-2,2-dimethylnaphtho...