15 documents found, page 1 of 2

Noite europeia dos investigadores em Armamar: palco da ciência em ambientes rurais

Genomic and phenotypic heterogeneity of Gardnerella genus – implications for wo...

Background: Gardnerella species have been associated with bacterial vaginosis but are also found in asymptomatic women [1]. Objective:Characterize Gardnerella urogenital isolates from asymptomatic women (HW) and women diagnosed with overactive bladder (OAB), to understand bacterial factors that may influence health outcomes. Methods: Gardnerella isolates (urine, n=5 HW, n=4 OAB) were subjected to WGS (Illu...

Noite europeia dos investigadores de Armamar: palco da ciência em ambientes rurais

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The success of particular acinetobacter baumannii clones: accumulating resistan...

In Portugal, carbapenem-resistant Acinetobacter baumannii (CRAB) has been associated with ST98, ST103 and ST208 (Oxford Scheme, Oxf) and a clone has usually been associated with a particular period of time. These clonal shifts were primarily explained by an increased antimicrobial resistance profile. Here we explore genomic and biochemical differences among these and more recent clones, which could further expl...

Extending the reservoir of bla IMP-5: the emerging pathogen Acinetobacter berez...

Acinetobacter bereziniae clinical relevance is starting to be recognized; however, very few descriptions of its carbapenem resistance currently exist. Here we characterize two carbapenem-resistant A. bereziniae isolates. Materials & methods: Isolates were obtained from environmental and clinical samples. Carbapenemases were searched by phenotypic, biochemical and PCR assays. Clonality was studied by ApaI-PFGE a...

Unsuitability of MALDI-TOF MS to discriminate Acinetobacter baumannii clones un...

MALDI-TOF MS (matrix-assisted laser desorption/ionization time-of-flight mass spectrometry) is now in the forefront for routine bacterial species identification methodologies, being its value for clonality assessment controversial. In this work we evaluated the potential of MALDI-TOF MS for assisting infection control by depicting Acinetobacter baumannii clones. Mass spectra of 58 A. baumannii clinical isolates...

Unveiling clones and integrons dynamics associated with carbapenemase-producing...

[Excerpt] Particular epidemic lineages (e.g. 235, 111, ST175 and 244) are associated with carbapenemase-producing P. aeruginosa (CPPA) isolates causing infections. Due to limited therapeutic options and possible carbapenemase spread, CPPA infections are of great concern. Nevertheless, the occurrence, genetic background and clonal dynamics over a long period of time of CPPA strains in Portuguese hospitals are un...

Diversity of non-clinical Acinetobacter species in a sub-saharan Africa region:...

[Excerpt] Although Acinetobacter baumannii has been the main agent for healthcare infections, recent reports suggest that some Acinetobacter environmental species should be considered as a potential cause of disease. In Angola, there are no previous data on its environmental reservoirs and resistance features. We aimed to unveil the occurrence and diversity of Acinetobacter species and the presence of resistanc...

Environmental reservoirs of Acinetobacter-producing carbapenem-hydrolysing clas...

Although Acinetobacter baumannii has been the main agent for healthcare infections, recent reports suggest that some Acinetobacter environmental species should be considered as a potential cause of disease. In Angola, an African country with an emerging economy, there are no previous data on Acinetobacter environmental reservoirs and resistance features. We aimed to investigate the occurrence and diversity of A...

Influx of enterococcus carrying antibiotic, copper and virulence resistance gen...

[abstract]