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Dupilumab Treatment in Atopic Dermatitis: Real-World Evidence from a Portuguese...

Pessoa e Costa, Tomás; Duarte, B.; Caldeira, M.; Rocha Páris, M.; Paiva-Lopes, M. J.

Introduction: Dupilumab is a fully human monoclonal antibody that blocks interleukin-4 and interleukin-13, key drivers of type 2 helper T-cell (Th2)-mediated inflammatory response. It was the first biologic treatment approved for adult patients with inadequately-controlled moderate-to-severe atopic dermatitis (AD). Continuous collection of daily data practice is important in order to evaluate the real effective...


A Dermatologia na Enfermaria de Medicina Interna: Análise Retrospectiva de um C...

Pessoa e Costa, Tomás; João, Ana Luísa; Pereira, Márcia; Estriga, Ana Rita; Rocha Páris, Filipa; Gomes da Silva, Eduardo

Background: Skin diseases are common in Internal Medicine wards and often require observation by a dermatologist. This study intends to characterize the pattern of skin pathology in these patients and to evaluate the impact of dermatologists in their approach. Methods: A retrospective study was conducted. Dermatology observations over 46 months in Internal Medicine wards of Hospital Santo António dos Capuchos w...


Five-Year Risk of Basal Cell Carcinoma Recurrence After a Conventional Surgical...

Duarte, Bruno; Vieira, Luis; Ribeiro, Luis; Pessoa e Costa, Tomás; João, Alexandre; Varanda, Alice; Cabete, Joana

Introduction: Basal cell carcinomas are mostly treated surgically, mostly by surgery with postoperative histopathologic margin evaluation (“conventional surgery”), but large long-term data regarding recurrence by completeness of excisions is limited. Methods: Retrospective cohort study of basal cell carcinomas treated by conventional surgery at different medical specialties in a large tertiary centre, between 2...


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