Sleep disorders are common in patients with Alzheimer's disease. These disorders are highly related to the cognitive impairment and have as main risk factor the time of disease. Additionally, they can damage the patient’s quality of life, as well as their family’s and caregivers’. The aim of this study was to clarify which changes in sleep patterns occur in patients with Alzheimer's disease and how they occur. ...
As metodologias ativas de ensino-aprendizagem são estratégias para integração de saberes e promoção de atitude crítica e reflexiva no ensino superior, podendo ser utilizadas em atividades de monitoria acadêmica, constituindo-se como um instrumento facilitador da compreensão e produção do conhecimento. O presente trabalho tem como objetivo relatar a experiência de monitores de um programa de monitoria acadêmica ...
Both psychological and neurological changes are related to deficits in communication and social interaction in patients diagnosed with autism spectrum disorder (ASD). There is evidence that fetuses are exposed to agrochemicals because some agrochemicals have the capacity to cross the blood-brain barrier, thus affecting the fetal central nervous system. The aim of the present study is to carry out a literature r...
Active teaching-learning methodologies are strategies for integrating knowledge and promoting critical and reflective attitude in higher education, and can be used in academic monitoring activities, constituting an instrument that facilitates the understanding and production of knowledge. This paper aims to report the experience of monitors of an academic monitoring program with the use of active methodologies ...
Medical Toxicology is recognized in Brazil as one of the 57 areas of medical practice. Until 2017, in the course of Medicine of the State University of Ceará (UECE), subjects related to intoxication, poisoning and accidents by venomous animals were approached in different disciplines, since Medical Toxicology was not part of the disciplines offered to the students. From the detection of this deficiency, it was ...
This study aimed to investigate the EEAm effect in mice models of nociception, inflammation and in behavioral tests evaluating the central nervous system. EEAm had inhibitory effects in the following tests: acetic acid-induced writhing (78%); formalin (62% - inflammatory phase); open field (46%). EEAm increased the nociceptive latency (56%) in tail flick test and increased the death-latency by 36% in the pentyl...
The species Protium heptaphyllum Aubl. March. belonging to the family Burseraceae is common in several areas of Brazil, where is known as almecega or white pitch. The plant is used popularly an anti-inflammatory and antiulcer. The objective of the present work was to study the pharmacological effects of a isomeric mixture of two triterpenes: alpha and beta amyrin (AMI) isolated from Protium heptaphyllum. The ph...
The mixture of alpha- and beta-amyrin (AMY) triterpenes was isolated from Protium heptaphyllum Aubl March (Burseraceae) which is a medicinal plant common to several Brazilian states and popularly known as “breu branco”. Although the literature presents several studies with these triterpenes, only a few of them emphasizes the CNS, and almost none were performed with triterpene acetylated derivatives. Then, the o...