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Cost-Utility Analysis of Denosumab Versus Zoledronic Acid in the Treatment of P...

Bragança, Fátima Carvalho; Augusto, Margarida; Jesus, Gonçalo; Paquete, Ana Teresa Martins; Cristino, Joaquim; Pereira, João

Introduction: Denosumab reduces the risk of osteoporosis fractures in post-menopausal women. Its cost and its added therapeutic value vs. zoledronic acid justify performing an economic evaluation in the Portuguese context. A societal perspective was adopted. Methods: A Markov model simulated the risk of osteoporosis fractures (hip, vertebrae, wrist and others) across patients’ lifetime, considering their clinic...

Date: 2019   |   Origin: Revista Portuguesa de Farmacoterapia
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