10 documents found, page 1 of 1
Aspirin but not statins is inversely related to gastric cancer with a duration–...
Pastorino, R; Pires Marafon, D; Sassano, M; Hoxhaj, I; Pelucchi, C; Liao, LM; Rabkin, CS; Sinha, R; Lunet, N; Morais, S; Zaridze, D; Maximovich, DBackground: Aspirin and statins have been suggested to have potential chemopreventive effects against gastric cancer (GC), although the results of previous studies have been inconsistent. This study therefore aimed to investigate the association between the use of aspirin and statins and GC. Methods: A pooled analysis of seven case-control studies within the Stomach Cancer Pooling Project, including 3220 cases ...
Reproductive factors, hormonal interventions, and gastric cancer risk in the St...
Song, M; Jayasekara, H; Pelucchi, C; Rabkin, CS; Johnson, KC; Hu, J; Palli, D; Ferraroni, M; Liao, LM; Bonzi, R; Zaridze, D; Maximovitch, D; Aragonés, NBackground: Gastric cancer incidence is higher in men, and a protective hormone-related effect in women is postulated. We aimed to investigate and quantify the relationship in the Stomach cancer Pooling (StoP) Project consortium. Methods: A total of 2,084 cases and 7,102 controls from 11 studies in seven countries were included. Summary odds ratios (ORs) and 95% confidence intervals (CIs) assessing associations...
Identifying the Profile of Helicobacter pylori-Negative Gastric Cancers: A Case...
Morais, S; Peleteiro, B; Araújo, N; Malekzadeh, R; Ye, W; Plymoth, A; Tsugane, S; Hidaka, A; Hamada, GS; López-Carrillo, L; Zaridze, D; Maximovich, DBackground: The prevalence of Helicobacter pylori-negative gastric cancer (HpNGC) can be as low as 1%, when infection is assessed using more sensitive tests or considering the presence of gastric atrophy. HpNGC may share a high-risk profile contributing to the occurrence of cancer in the absence of infection. We estimated the proportion of HpNGC, using different criteria to define infection status, and compared...
Inverse Association between Dietary Iron Intake and Gastric Cancer: A Pooled An...
Collatuzzo, G; Teglia, F; Pelucchi, C; Negri, E; Rabkin, CS; Liao, LM; Sinha, R; López‐carrillo, L; Lunet, N; Morais, S; Aragonés, N; Moreno, VBackground: Inconsistent findings have been reported regarding the relationship between dietary iron intake and the risk of gastric cancer (GC). Methods: We pooled data from 11 case‐control studies from the Stomach Cancer Pooling (StoP) Project. Total dietary iron intake was derived from food frequency questionnaires combined with national nutritional tables. We derived the odds ratios (ORs) and 95% confidence ...
Coffee consumption and gastric cancer: A pooled analysis from the Stomach cance...
Martimianaki, G; Bertuccio, P; Alicandro, G; Pelucchi, C; Bravi, F; Carioli, G; Bonzi, R; Rabkin, CS; Liao, LM; Sinha, R; Johnson, K; Hu, J; Palli, DObjective This study aimed to evaluate and quantify the relationship between coffee and gastric cancer using a uniquely large dataset from an international consortium of observational studies on gastric cancer, including data from 18 studies, for a total of 8198 cases and 21 419 controls. Methods A two-stage approach was used to obtain the pooled odds ratios (ORs) and the corresponding 95% confidence intervals ...
Family History and Gastric Cancer Risk: A Pooled Investigation in the Stomach C...
Vitelli-Storelli, F; Rubín-García, M; Pelucchi, C; Benavente, Y; Bonzi, R; Rota, M; Palli, D; Ferraroni, M; Lunet, N; Morais, S; Ye, W; Plymoth, AAlthough there is a clear relationship between family history (FH) and the risk of gastric cancer (GC), quantification is still needed in relation to different histological types and anatomical sites, and in strata of covariates. The objective was to analyze the risk of GC according to first-degree FH in a uniquely large epidemiological consortium of GC. This investigation includes 5946 cases and 12,776 control...
Polyphenol Intake and Gastric Cancer Risk: Findings from the Stomach Cancer Poo...
Vitelli-Storelli, F; Rossi, M; Pelucchi, C; Rota, M; Palli, D; Ferraroni, M; Lunet, N; Morais, S; López-Carrillo, L; Zaridze, DG; Maximovich, DPhenolic compounds may exert a favorable effect on the risk of several cancer types, including gastric cancer (GC). However, selected polyphenol classes have not been adequately investigated in relation to GC. The aim of this study is to evaluate the association between the intake of polyphenols in relation to GC risk. We used data from the Stomach cancer Pooling (StoP) Project, including 10 studies from six co...
Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) pro...
Ferro, A; Rosato, V; Rota, M; Costa, AR; Morais, S; Pelucchi, C; Johnson, KC; Hu, J; Palli, D; Ferraroni, M; Zhang, ZF; Bonzi, R; Yu, GP; Peleteiro, BThe consumption of processed meat has been associated with noncardia gastric cancer, but evidence regarding a possible role of red meat is more limited. Our study aims to quantify the association between meat consumption, namely white, red and processed meat, and the risk of gastric cancer, through individual participant data meta-analysis of studies participating in the “Stomach cancer Pooling (StoP) Project”....
Smoking and Helicobacter pylori infection: an individual participant pooled ana...
Ferro, A; Morais, S; Pelucchi, C; Aragonés, N; Kogevinas, M; López-Carrillo, L; Malekzadeh, R; Tsugane, S; Hamada, GS; Hidaka, A; Hernández-Ramírez, RUSmoking has been associated with acquisition and increased persistence of Helicobacter pylori infection, as well as with lower effectiveness of its eradication. A greater prevalence of infection among smokers could contribute to the increased risk for gastric cancer. We aimed to estimate the association between smoking and seropositivity to H. pylori through an individual participant data pooled analysis using ...
The stomach cancer pooling (StoP) project: study design and presentation
Pelucchi, C; Lunet, N; Boccia, S; Zhang, ZF; Praud, D; Boffetta, P; Levi, F; Matsu, K; Ito, H; Hu, J; Johnson, KC; Ferraroni, M; Yu, GP; Peleteiro, BGastric cancer affects about one million people per year worldwide, being the second leading cause of cancer mortality. The study of its etiology remains therefore a global issue as it may allow the identification of major targets, besides eradication of Helicobacter pylori infection, for primary prevention. It has however received little attention, given its comparatively low incidence in most high-income coun...