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Antibacterial, antibiofilm and cytotoxic activities of Terminalia fagifolia Mar...

Araujo, Alyne Rodrigues de; Quelemes, Patrick Veras; Perfeito, Márcia Luana Gomes; Lima, Luiza Ianny de; Sá, Melka Coêlho; Nunes, Paulo Humberto Moreira

Background: The methicillin resistance of bacteria from the genus Staphylococcus and its ability to form biofilms are important factors in pathogenesis of these microorganisms. Thus, the search for new antimicrobials agents, especially from plants, has been intensified. In this context, Terminalia species have been the subject of research for many pharmacological activities. In this study we evaluated the antib...

Date: 2021   |   Origin: Oasisbr

Acetylated cashew gum and fucan for incorporation of lycopene rich extract from...

Andrades, Eryka Oliveira de; Costa, João Marcos Antônio Rodrigues da; Neto, Francisco Edmar Moreira de Lima; Araujo, Alyne Rodrigues de

Industrial application of lycopene is limited due to its chemical instability and low bioavailability. This study proposes the development of fucan-coated acetylated cashew gum nanoparticles (NFGa) and acetylated cashew gum nanoparticles (NGa) for incorporation of the lycopene-rich extract from red guava (LEG). Size, polydispersity, zeta potential, nanoparticles concentration, encapsulation efficiency, transmis...


Identification of Eschweilenol C in derivative of Terminalia fagifolia Mart. an...

Araujo, Alyne Rodrigues de; Ramos-Jesus, Joilson; Oliveira, Taiane Maria de; Carvalho, Andressa Maria A. de; Nunes, Paulo Humberto M.

A green synthetic route was developed to prepare silver nanoparticles (AgNPs) in aqueous solution for biological applications. Eschweilenol C, a compound derivative ellagic acid was identified as the main constituent of the aqueous fraction of the ethanolic extract of Terminalia fagifolia Mart. by NMR analysis. In the green synthesis, the ethanolic extract of T. fagifolia and its aqueous fraction were used to p...


Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagoni...

Marani, Mariela M.; Perez, Luis O.; Araujo, Alyne Rodrigues de; Plácido, Alexandra; Sousa, Carla F.; Quelemes, Patrick Veras; Oliveira, Mayara

Patagonia's biodiversity has been explored from many points of view, however, skin secretions of native amphibians have not been evaluated for antimicrobial peptide research until now. In this sense, Pleurodema thaul is the first amphibian specie to be studied from this large region of South America. Analysis of cDNA-encoding peptide in skin samples allowed identification of four new antimicrobial peptides. The...


Thaulin-1: The first antimicrobial peptide isolated from the skin of a Patagoni...

Marani, Mariela M.; Perez, Luis O.; Araujo, Alyne Rodrigues de; Plácido, Alexandra; Sousa, Carla F.; Quelemes, Patrick Veras; Oliveira, Mayara

Patagonia's biodiversity has been explored frommany points of view, however, skin secretions of native amphibians have not been evaluated for antimicrobial peptide research until now. In this sense, Pleurodema thaul is the first amphibian specie to be studied from this large region of South America. Analysis of cDNA-encoding peptide in skin samples allowed identification of four new antimicrobial peptides. The ...


Characterization and Biological Activities of Ocellatin Peptides from the Skin ...

Marani, Mariela Mirta; Dourado, Flávio Santos; Quelemes, Patrick Veras; Araujo, Alyne Rodrigues de; Perfeito, Márcia Luana Gomes; Barbosa, Eder Alves

Eight new peptides were isolated from the skin secretion of the frog Leptodactylus pustulatus and their amino acid sequences determined by de novo sequencing and by cDNA cloning. Structural similarities between them and other antimicrobial peptides from the skin secretion of Leptodactylus genus frogs were found. Ocellatins-PT1 to -PT5 (25 amino acid residues) are amidated at the C-terminus, while ocellatins-PT6...


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