Made available in DSpace on 2019-10-04T12:37:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-04-04; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundacao de Amparoa Pesquisa do Estado de Sao Paulo; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Chitosan-tripolyphosphate (CS-TPP) nanoparticles containing naproxen (NPX) were dispersed in poloxamer (PL) as u...
Purpose The anionic form of the drug mefenamic acid intercalated into the nanocarrier layered double hydroxide (LDH-Mef) was evaluated by anti-inflammatory and antinociceptive assays. Methods The LDH-Mef material was characterized by a set of physicochemical techniques, which was supported by Density Functional Theory calculations. The pharmacological effects of LDH-Mef (40 wt% of drug) were evaluated by hemoly...