3 documents found, page 1 of 1
Isolamento e identificação de mimetopos de auto-antígenos para utilização em im...
Araujo, Galber RodriguesCoordenação de Aperfeiçoamento de Pessoal de Nível Superior; CHAPTER 2: Juvenile Idiopathic Arthritis (JIA) is a set of chronic diseases characterized by persistent inflammation of joints. "Idiopathic" means that no one knows the cause of illness and "Juvenile" in this case means that the onset of symptoms occurs before 16 years of age. The diagnosis of JIA is clinical and is based on the finding of arthritis i...
Epítopos miméticos e autoantígenos aplicados ao imunodiagnóstico da artrite reu...
Araujo, Galber RodriguesCoordenação de Aperfeiçoamento de Pessoal de Nível Superior; Introduction: Rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) are autoimmune rheumatic diseases of unknown cause characterized by inflammation, which can cause joint damage, and in some cases, damage to other parts of the body. To date, there is no single, definitive test for the diagnosis of RA and JIA, which is based on patient his...
Improved serological detection of rheumatoid arthritis: a highly antigenic mimo...
Araujo, Galber Rodrigues; Vaz, Emília Rezende; Fujimura, Patricia Tiemi; Fonseca, João Eurico; de Lima, Lucélia Maria; Canhao, HelenaIntroduction: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that affects around 1% of the human population worldwide. RA diagnosis can be difficult as there is no definitive test for its detection. Therefore, the aim of this study was to identify biomarkers that could be used for RA diagnosis. Methods: Sera from a collagen-induced arthritis mouse model were used to select potential biom...