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Óleos essenciais como repelentes de insetos: produtos comercializados online e ...

Araujo, Ines; Pereira , Daniela; Pinho , Cláudia; Correia, Patrícia

Introdução: O uso de repelentes sintéticos e naturais, tem vindo a aumentar, principalmente devido às doenças virais emergentes transmitidas por vetores como a Dengue, Zika, Febre Amarela e Malária. Os óleos essenciais (OE) são líquidos concentrados com compostos voláteis, produzidos por plantas e com funções de defesa ou comunicação. A tendência atual é recorrer ao uso de repelentes naturais como os OE, que ap...


Matrisomal components involved in regenerative wound healing in axolotl and aco...

Avila-Martinez, Nancy; Gansevoort, Merel; Verbakel, Juul; Jayaprakash, Haarshaadri; Araujo, Ines; Vitorino, Marta; Tiscornia, Gustavo

Achieving regeneration in humans has been a long-standing goal of many researchers. Whereas amphibians like the axolotl (Ambystoma mexicanum) are capable of regenerating whole organs and even limbs, most mammals heal their wounds via fibrotic scarring. Recently, the African spiny mouse (Acomys sp.) has been shown to be injury resistant and capable of regenerating several tissue types. A major focal point of res...


New fluorescent probes based on gallium(III) corrole complexes for the recognit...

Santos, Carla I.M.; Santiago, Ana M.; Araújo, Ana R.L.; Pinto, Sandra; Agostinho, Rafaela; Simão, Sónia; Azevedo, Tomás Pais de; Antunes, Catarina

In this work, three fluorescent probes for detection of hydrogen sulfide (H2S) where prepared based on gallium (III) corrole complexes bearing nitro groups at beta-pyrrolic positions. Two of the compounds selected, the 3-nitro5,10,15- tris(pentafluorophenyl)corrolatogallium(III)(pyridine) (CGa-NO2) and the 3,17-dinitro-5,10,15-tris (pentafluorophenyl)corrolatogallium(III)(pyridine) (CGa-2NO2) present one and tw...


Rewired glycosylation activity promotes scarless regeneration and functional re...

Nogueira-Rodrigues, Joana; Leite, Sérgio C.; Pinto-Costa, Rita; Sousa, Sara C.; Luz, Liliana L.; Sintra, Maria A.; Oliveira, Raquel; Monteiro, Ana C.

Regeneration of adult mammalian central nervous system (CNS) axons is abortive, resulting in inability to recover function after CNS lesion, including spinal cord injury (SCI). Here, we show that the spiny mouse (Acomys) is an exception to other mammals, being capable of spontaneous and fast restoration of function after severe SCI, re-establishing hind limb coordination. Remarkably, Acomys assembles a scarless...


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