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Perezone, from the gorgonian Pseudopterogorgia rigida, induces oxidative stress...
Abreu,Paula A.; Wilke,Diego V.; Araujo,Ana J.; Marinho-Filho,José Delano B.; Ferreira,Elthon G.; Ribeiro,Carlos Margo R.; Pinheiro,Leandro S.Abstract Four bisabolanes 1–4, including perezone (1) and triacetyl perezone (2), were isolated through a bioassay-guided fractionation of the extract obtained from the Caribbean gorgonian coral Pseudopterogorgia rigida collected during an expedition cruise to the Bahamas. All isolated compounds showed to be cytotoxic toward panel of four human tumor cell lines, as quantified by the MTT assay after 72 h incubat...
Date: 2015
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Origin: Oasisbr