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Secretory IgA and T Cells Targeting SARS-CoV-2 Spike Protein Are Transferred to...

Gonçalves, J; Juliano, AM; Charepe, N; Alenquer, M; Athayde, D; Ferreira, F; Archer, M; Amorim, MJ; Serrano, F; Soares, H

In view of the scarcity of data to guide decision making, we evaluated how BNT162b2 and mRNA-1273 vaccines affect the immune response in lactating women and the protective profile of breastmilk. Compared with controls, lactating women had a higher frequency of circulating RBD memory B cells and higher anti-RBD antibody titers but similar neutralizing capacity. We show that upon vaccination, immune transfer to b...

Date: 2021   |   Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
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