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Effectiveness of biofeedback-assisted asynchronous telerehabilitation in muscul...

Janela, Dora; Costa, Fabíola; Weiss, Brandon; Areias, Anabela C.; Molinos, Maria; Scheer, Justin K; Laíns, Jorge; Bento, Virgílio; Cohen, Steven P.

Background: Musculoskeletal conditions are the leading cause of disability worldwide. Telerehabilitation may be a viable option in the management of these conditions, facilitating access and patient adherence. Nevertheless, the impact of biofeedback- assisted asynchronous telerehabilitation remains unknown. Objective: To systematically review and assess the effectiveness of exercise-based asynchronous biofeedba...


Engagement and Utilization of a Complete Remote Digital Care Program for Muscul...

Scheer, Justin; Areias, Anabela C.; Molinos, Maria; Janela, Dora; Moulder, Robert; Laíns, Jorge; Bento, Virgílio; Yanamadala, Vijay

Background: Musculoskeletal (MSK) conditions are the number one cause of disability worldwide. Digital care programs (DCPs) for MSK pain management have arisen as alternative care delivery models to circumvent challenges in accessibility of conventional therapy. Despite the potential of DCPs to reduce inequities in accessing care, the outcomes of such interventions in rural and urban populations have yet to be ...


The potential of a multimodal digital care program in addressing healthcare ine...

Areias, Anabela C.; Molinos, Maria; Moulder, Robert G.; Janela, Dora; Scheer, Justin K.; Bento, Virgílio; Yanamadala, Vijay; Cohen, Steven P.

Digital interventions have emerged as a solution for time and geographical barriers, however, their potential to target other social determinants of health is largely unexplored. In this post-hoc analysis, we report the impact of social deprivation on engagement and clinical outcomes after a completely remote multimodal musculoskeletal (MSK) digital care program managed by a culturally-sensitive clinical team. ...


Current and emerging techniques for diagnosis and MRD detection in AML: a compr...

Teixeira, Alexandra; Carreira, Luís; Abalde-Cela, Sara; Sampaio-Marques, Belém; Areias, Anabela C.; Ludovico, Paula; Diéguez, Lorena

Acute myeloid leukemia (AML) comprises a group of hematologic neoplasms characterized by abnormal differentiation and proliferation of myeloid progenitor cells. AML is associated with poor outcome due to the lack of efficient therapies and early diagnostic tools. The current gold standard diagnostic tools are based on bone marrow biopsy. These biopsies, apart from being very invasive, painful, and costly, have ...


Surface roughness dependent osteoblast and fibroblast response on poly(l-lactid...

Ribeiro, Clarisse; Sencadas, Vítor João Gomes Silva; Areias, Anabela C.; Gama, F. M.; Lanceros-Méndez, S.

Poly(l-lactide) electrospun mats with random and aligned fiber orientation and films have been produced with degrees of crystallinity ranging from 0 up to nearly 50%. The overall surface roughness is practically constant irrespective of the sampling areas (1 × 1 µm to 20 × 20 µm) for degrees of crystallinity below 30%, increasing for higher degrees of crystallinity for the larger sampling areas. Further, due to...


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