14 documents found, page 1 of 2
Association between blood pressure and angiotensin-converting enzymes activity ...
Gaspar, AR; Andrade, B; Mosca, S; Ferreira-Duarte, M; Teixeira, A; Cosme, D; Albino-Teixeira, A; Ronchi, FA; Leite, AP; Casarini, DE; Areias, JCObjectives:Angiotensin-converting enzymes' (ACEs) relationship with blood pressure (BP) during childhood has not been clearly established. We aimed to compare ACE and ACE2 activities between BMI groups in a sample of prepubertal children, and to characterize the association between these enzymes' activities and BP.Methods:Cross-sectional study of 313 children aged 8-9 years old, included in the birth cohort Gen...
From Illness to Resilience: Mediating Factors of Quality of Life in Patients wi...
Moedas, F; Nunes, F; Brito, P; Bessa, A; Espirito Santo, S; Soares, S; Pereira, M; Viana, Victor; Peixoto, B; Miranda, JO; Areias, JC; Areias, MEG
Impact of physical activity on redox status and nitric oxide bioavailability in...
Leite-Almeida, L; Morato, M; Cosme, D; Afonso, J; Areias, JC; Guerra, A; Caldas, Afonso, A; Albino-Teixeira, A; Sousa, T; Correia-Costa, LNutritional status might contribute to variations induced by physical activity (PA) in redox status biomarkers. We investigated the influence of PA on redox status and nitric oxide (NO) production/metabolism biomarkers in nonoverweight and overweight/obese prepubertal children. We performed a cross-sectional evaluation of 313 children aged 8-9 years (163 nonoverweight, 150 overweight/obese) followed since birth...
Gender differences in the effect of adiposity on markers of cardiovascular risk...
Leal, DA; Correia-Costa, L; Moura, C; Mota, C; Correia-Costa, A; Areias, JC; Guerra, A; Afonso, AC; Azevedo, AINTRODUCTION: In the last years, evidence has started to emerge on the presence of cardiometabolic differences between genders before puberty. This study aims to evaluate if the association between obesity and markers of cardiovascular risk is different between genders in 8 to 9-year-olds. METHODS: Cross sectional study of 315 children (167 boys) aged 8-9 years old, followed in the birth cohort Generation XXI (...
Maternal Diabetes Mellitus as a Risk Factor for High Blood Pressure in Late Chi...
Miranda, JO; Cerqueira, RJ; Barros, H; Areias, JCIntrauterine fetal conditions can have lifelong cardiovascular effects. The impact of maternal diabetes mellitus on children’s cardiovascular profile is not well established. The goal of this study was to explore the association between maternal diabetes mellitus and offspring’s blood pressure (BP) ≤10 years of age. Generation XXI is a prospective birth cohort, which enrolled 8301 mother-offspring pairs, includ...
Neurocognitive profiles in adolescents and young adults with congenital heart d...
Areias, ME; Peixoto, B; Santos, I; Cruz, L; Regadas, A; Pinheiro, C; Monteiro, H; Araújo, S; Carvalho, T; Miranda, J; Moura, C; Soares, J; Viana, VictorIntroduction and Objectives: The objectives of this study were to assess the neuropsychological performance (NP) of adolescents and young adults with congenital heart disease (CHD), comparing them with a group of healthy controls, to determine whether there are different neurocognitive phenotypes in CHD, and to identify their relation to sociodemographic, neonatal, clinical and psychological adjustment variable...
Longer duration of obesity is associated with a reduction in urinary angiotensi...
Morato, M; Correia-Costa, L; Sousa, T; Cosme, D; Schaefer, F; Areias, JC; Guerra, A; Afonso, AC; Barros, H; Azevedo, A; Albino-Teixeira, ABackground: We aimed to study the impact of obesity on urinary excretion of angiotensinogen (U-AGT) in prepubertal children, focusing on the duration of obesity and gender. Also, we aimed to evaluate whether plasma angiotensinogen (P-AGT) and hydrogen peroxide (H2O2) play a role in the putative association. Methods: Cross-sectional evaluation of 305 children aged 8–9 years (160 normal weight, 86 overweight, and...
Association of myeloperoxidase levels with cardiometabolic factors and renal fu...
Costa, L; Sousa, T; Morato, M; Cosme, D; Afonso, J; Moura, C; Mota, C; Areias, JC; Guerra, A; Schaefer, F; Afonso, AC; Barros, H; Albino-Teixeira, AINTRODUCTION: Myeloperoxidase (MPO), an enzyme linking obesity and cardiovascular (CV) risk in adults, has rarely been studied in young children and no studies assessed its association with renal function. We sought to explore a possible association between serum MPO levels, obesity, CV risk factors and renal function in prepubertal children. MATERIALS/METHODS: Cross-sectional evaluation of 309 children aged 8-...
Determinants of carotid-femoral pulse wave velocity in prepubertal children
Correia-Costa, A; Correia-Costa, L; Caldas-Afonso, A; Schaefer, F; Guerra, A; Moura, C; Mota, C; Barros, H; Areias, JC; Azevedo, ABACKGROUND: Pulse wave velocity (PWV) is a noninvasive technique to evaluate arterial stiffness, a dynamic property of the vessels, reflecting their structure and function. Childhood obesity is associated with several cardiovascular comorbidities and to the progression of atherosclerosis. We aimed to compare carotid-femoral PWV between normal weight and overweight/obese prepubertal children and to quantify its ...
Accelerated growth during childhood is associated with increased arterial stiff...
Pais, C; Correia-Costa, L; Moura, C; Mota, C; Severo, M; Guerra, A; Areias, JC; Schaefer, F; Caldas-Afonso, C; Barros, H; Santos, AC; Azevedo, A