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Antenatal vitamin A administration attenuates lung hypoplasia by interfering wi...

Baptista, Maria J.; Rocha, Gustavo Filipe Melo Alves; Pedrosa, Carla; Gonzaga, Sílvia; Teles, Antónia; Estevão-Costa, José; Areias, José C.

Early and late lung underdevelopment in congenital diaphragmatic hernia (CDH) is likely caused by nonmechanical (directly mediated by nitrofen) and mechanical (mediated by thoracic herniation) factors, respectively. The authors investigated if vitamin A enhances lung growth because of effects on both early and late determinants of lung hypoplasia. Background/Purpose Early and late lung underdevelopment in conge...


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