23 documents found, page 1 of 3
Can maternal exposure to tamoxifen compromise sperm and behavioural parameters ...
de Matos Manoel, Beatriz; da Silva Moreira, Suyane [UNESP]; Zampieri, Gabriela Morelli [UNESP]; Machado Pinheiro, Luísa [UNESP]Made available in DSpace on 2022-04-29T08:38:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Tamoxifen, a selective non-steroidal estrogen receptor modulator, is the standard adjuvant endocrine treatment for breast cancer. Since information on the risk of using tamoxifen during pregnancy is still scarce, this study evaluated whether the in utero and lactational treatment with this drug could co...
Safety assessment of the ethanolic extract from Piper vicosanum yunck leaves in...
Jorge, Bárbara Campos [UNESP]; Júnior, Armando Jorge; Stein, Julia [UNESP]; Reis, Ana Carolina Casali [UNESP]; Moreira, Suyane da Silva [UNESP]Made available in DSpace on 2022-04-29T08:40:17Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Background: Piper vicosanum (Piperaceae) is a species used in folk medicine mainly due to its anti-inflammatory and analgesic properties. However, the data available about its safety are still insufficient. Purpose: This study evaluated the ...
Toxicological evaluation of ethanolic extract of leaves from Doliocarpus dentat...
Branquinho, Lidiane Schultz; Verdan, Maria Helena; dos Santos, Elisangela; Macorini, Luis Fernando Benitez; Maris, Rafael SouzaMade available in DSpace on 2022-05-01T09:47:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Doliocarpus dentatus (Dilleniaceae) has been used in folk medicine to treat inflammation and pain; however, studies evaluating its toxicity potential, as well as its effects on anxiety and depression, are scarce. This study investigated the toxicological profile of an ethanolic extract from leaves of D....
Evaluation of the safety of ethanolic extract from Piper amalago L. (Piperaceae...
Stein, Julia [UNESP]; Jorge, Bárbara Campos [UNESP]; Casali Reis, Ana Carolina [UNESP]; Santos Radai, Joyce Alencar; da Silva Moreira, Suyane [UNESP]Made available in DSpace on 2022-05-01T12:40:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Piper amalago L. (Piperaceae) is traditionally used due to its anti-inflammatory, analgesic, diuretic, and antiparasitic properties. However, few studies have focused on its adverse effects, compromising its safe use. This study evalu...
Toxicological analysis and efficacy of 2-phenylchromone on mycobacteria viabili...
Moreira, Flora Martinez Figueira; Radai, Joyce Alencar Santos; de Souza, Vanessa Vilamaior; Berno, Claudia Rodrigues; de Araújo, Flavio Henrique SouzaMade available in DSpace on 2022-05-01T15:13:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; Background: Studies have reported that compounds similar to flavone present antimicrobial and anti-inflammatory properties; however these effects are poorly described in the context of mycobacterium infection. Purpose: This study investigated the efficacy of 2-phenylchromone (Flavone) on mycobacteria vi...
Ibuprofen compromises sexual behavior and fertility in female rats exposed duri...
Jorge, Bárbara Campos [UNESP]; Balin, Paola da Silva [UNESP]; Carneiro, Giovanna de Brito [UNESP]; Belleti, Rafael [UNESP]Made available in DSpace on 2021-06-25T10:34:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-10-20; The influence of ibuprofen exposure during the perinatal period, when the brain sexual differentiation process occurs, on the sexual behavior and fertility of female offspring Wistar rats has been evaluated. Ibuprofen was orally administered to the dams at doses of 0, 10, 30 or 60 mg/kg during the gesta...
Effects of benzo(a)pyrene at environmentally relevant doses on embryo-fetal dev...
da Silva Moreira, Suyane [UNESP]; de Lima Inocêncio, Leonardo Cesar [UNESP]; Jorge, Bárbara Campos [UNESP]; Reis, Ana Carolina Casali [UNESP]Made available in DSpace on 2021-06-25T10:47:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Studies have demonstrated that Benzo(a)Pyrene (BaP), a polycyclic aromatic hydrocarbon ubiquituous in the environment, can cause teratogenic effects. Since the majority of ...
Parental exposure to benzo(a)pyrene in the peripubertal period impacts reproduc...
Jorge, Bárbara Campos [UNESP]; Reis, Ana Carolina Casali [UNESP]; Stein, Julia [UNESP]; Balin, Paola da Silva [UNESP]; Sterde, Érika Tissiana [UNESP]Made available in DSpace on 2021-06-25T10:50:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Benzo(a)pyrene (BaP) is an ubiquitous environmental pollutant which can lead to adverse effects on male reproduction. However, the persistence of these changes on a multigenerational scale has not been sufficiently explored. This study...
Antiarthritic and Antihyperalgesic Properties of Ethanolic Extract from Gomphre...
MacOrini, Luis Fernando Benitez; Radai, Joyce Alencar Santos; Maris, Rafael Souza; Silva-Filho, Saulo Euclides; Leitao, Maicon MatosMade available in DSpace on 2021-06-25T11:05:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Gomphrena celosioides Mart. (Amaranthaceae) is used in folk medicine as a natural analgesic, and in Brazil, the species of genus Gomphrena is used for rheumatism. However, scientific evidence which supports its popular use as an analgesic is scarce. This study assessed the antiarthritic and antihyperalg...
Analgesic and anti-inflammatory articular effects of essential oil and camphor ...
dos Santos, Elisangela; Leitão, Maicon Matos; Aguero Ito, Caren Naomi; Silva-Filho, Saulo Euclides; Arena, Arielle Cristina [UNESP]Made available in DSpace on 2021-06-25T11:09:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-06; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul; Ethnopharmacological relevance: Leaves from Ocimum kilimandscharicum Gürke (Lamiaceae) are popularly used against articular pain. Aim...