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The effects of histone deacetylase inhibition on the levels of cerebral cytokin...
Valvassori, Samira S.; Resende, Wilson R.; Varela, Roger B.; Arent, Camila O.; Gava, Fernanda F.; Peterle, Bruna R.; Dal-Pont, Gustavo C.Studies have suggested the involvement of inflamma- tory processes in the physiopathology of bipolar disorder. Preclinical evidences have shown that histone deacetylase inhib- itors may act as mood-stabilizing agents and protect the brain in models of mania and depression. The aim of the present study was to evaluate the effects of sodium butyrate (SB) and valproate (VPA) on behavioral changes, histone deacetyl...
Data: 2017
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Origem: Oasisbr