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Impact of Bariatric Surgery on Long-term Cardiovascular Risk: Comparative Effec...

Oliveira, SC; Neves, JS; Souteiro, P; Pedro, J; Magalhães, D; Guerreiro, V; Bettencourt-Silva, R; Costa, MM; Varela, A; Barroso, I; Freitas, P

Introduction: Several reports highlight bariatric surgery as an efficient and long-lasting strategy for weight loss. Herein, we aimed to evaluate the impact of bariatric surgery on 10-year cardiovascular disease (CVD) risk and to compare the effectiveness of different surgical procedures, employing the Framingham Risk Score (FRS). Methods: Retrospective longitudinal observational study of patients undergoing ba...


Preoperative thyroid function and weight loss after bariatric surgery

Neves, JS; Souteiro, P; Oliveira, SC; Pedro, J; Magalhães, D; Guerreiro, V; Costa, MM; Bettencourt-Silva, R; Santos, AC; Queirós, J; Varela, A

Thyroid function has an important role on body weight regulation. However, the impact of thyroid function on weight loss after bariatric surgery is still largely unknown. We evaluated the association between preoperative thyroid function and the excess weight loss 1 year after surgery, in 641 patients with morbid obesity who underwent bariatric surgery. Patients with a history of thyroid disease, treatment with...


Amiodarone-induced thyrotoxicosis in a pediatric patient: A rare and demanding ...

Oliveira, SC; Marques, B; Laranjo, S; Lopes, L

Thyroid dysfunction is one of the most common adverse effects of amiodarone therapy, ranging from subclinical changes to overt clinical thyrotoxicosis (AIT) and/or hypothyroidism. Due to its heterogeneity, AIT lasts as a defiant entity, leading to a thorny treatment course, particularly in pediatrics. AIT can be classified as either type 1, type 2 or mixed form based on its pathophysiology. Differentiating betw...


Prevalence and determinants of painful and painless neuropathy in type 1 diabet...

Barbosa, M; Saavedra, A; Oliveira, SC; Reis, L; Rodrigues, F; Severo, M; Sittl, R; Maier, C; Carvalho, D

Aims: To evaluate (1) the prevalence of diabetic distal symmetrical sensory-motor polyneuropathy (DSPN) and painful DSPN among patients with type 1 diabetes mellitus (DM1) aged over 18 years and (2) the determinant factors of neuropathy and pain in those patients. Materials and Methods: An epidemiological, cross-sectional, observational study was performed; 330,386 people were included, and a total of 444 peopl...


Long-Term weight loss and metabolic syndrome remission after bariatric surgery:...

Guerreiro, V; Neves, JS; Salazar, D; Ferreira, MJ; Oliveira, SC; Souteiro, P; Pedro, J; Magalhães, D; Varela, A; Belo, S; Freitas, P; Carvalho, D

Introduction: Bariatric surgery is an effective treatment for morbid obesity and its metabolic related comorbidities. However, the literature reports inconsistent results regarding weight loss (WL) and the resolution of comorbidities associated with obesity. Objective: We aim to evaluate long-Term differences in WL between different surgical techniques and the impact of each surgical technique on metabolic para...


Assessing the Effects of the Transition from Multiple Daily Insulin Injections ...

Oliveira, SC; Neves, C; Esteves, C; Neves, JS; Oliveira, AI; Pereira, M; Arteiro, Cristina; Costa, A; Redondo, MD; Baltazar, R; Carvalho, Davide

Introduction: Intensive insulin therapy is currently the main treatment in type I diabetes mellitus (DM) which includes multiple daily insulin injections (MDI) and continuous subcutaneous insulin infusion (CSII). The latter has become the preferred therapeutic mode, since it better mimics the physiological pancreatic action, althought there is limited evidence that supports its superiority to MDI. The aim of ou...


Ectopic Cushing's Syndrome Unveiling a Metastatic Parotid Carcinoma

Oliveira, SC; Neves, JS; Souteiro, P; Belo, S; Oliveira, AI; Moreira, H; Gomes, PM; Coelho, L; Sarmento, C; Fonseca, E; Neves, C; Freitas, P

Introduction. Adrenocorticotropic hormone (ACTH) ectopic production is a rare cause of Cushing syndrome (CS). The most commonly associated tumours are small-cell lung carcinoma along with bronchial and thymic carcinoids. To date, only 5 cases have been published in the literature featuring ectopic ACTH secretion from metastatic acinic cell carcinoma (ACC) of the parotid gland. We hereby describe a very uncommon...


Effect of Weight Loss after Bariatric Surgery on Thyroid-Stimulating Hormone Le...

Neves, JS; Oliveira, SC; Souteiro, P; Pedro, J; Magalhães, D; Guerreiro, V; Bettencourt-Silva, R; Costa, MM; Santos, AC; Queirós, J; Varela, A

Background: Several studies have reported that morbid obesity is associated with increased thyroid-stimulating hormone (TSH) levels. However, it is not clear what is the impact of bariatric surgery on postoperative thyroid function. The aim of this study was to evaluate the effect of weight loss after bariatric surgery on TSH levels in euthyroid patients with morbid obesity. Methods: We performed a retrospectiv...


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