The present paper contemplates the ground of research on emerging forms of inhabiting spaces in contemporary urban territories, with a precise focus on Macau’s 1960s housing production.In order to settle a comprehensive understanding about inaugural statements of architectural modernity, in the field of modern housing, built in Pearl River Delta’s region as a hybrid interpretation of Modern Movement’s ideas in ...
Homologous recombination repair (HRR) is the cellular mechanism for error-free repair of DNA double-strand breaks. Pathogenic germline variants in BRCA1 and BRCA2 lead to HRR deficiency associated with breast, ovarian, prostate, pancreatic cancers and are sensitive to PARP inhibitors (PARPi). Defects in HRR genes beyond BRCA1/2 could also result in HRR deficiency and sensitize the tumor to PARPi, thus expanding...