8 documents found, page 1 of 1

Inclusion of Optic Nerve Assessed by Visual Evoked Potentials in Dissemination ...

Introduction: Optic nerve (ON) inclusion as the fifth location in dissemination in space (DIS) for the diagnosis of multiple sclerosis (MS) was proposed in 2016 by the Magnetic Resonance Imaging in Multiple Sclerosis Group. However, there was insufficient evidence to include this recommendation in the 2017 revision of McDonald criteria. Our objective was to investigate the effect of including ON involvement ass...

Immune response after vaccination or natural infection with pandemic influenza ...

Sequence analysis of resistance markers in pandemic influenza A (H1N1) 2009 vir...

Backround: In April 2009, a new influenza A (H1N1) virus (AH1N1pdm) was detected circulating in humans. Its rapid widespread transmission led to the declaration by the WHO of an influenza pandemic. This virus had origin in a reassortment between a North American swine lineage (already a triple reassortant, circulating in pigs since the late 1990’s) and a Eurasian swine lineage (which contributed to the AH1N1pdm...

Antigenic and genetic analysis of pandemic influenza A(H1N1) 2009 viruses from ...

Backround: The influenza AH1N1 2009 pandemic virus (AH1N1pdm) was first detected in Portugal in May 4th 2009. This virus had origin in a reassortment between a North American swine lineage (already a triple reassortant, circulating in pigs since the late 1990’s) and a Eurasian swine lineage. As the HA (North American swine lineage) continues to circulate in the human population, its antigenic sites will continu...

Seasonal and pandemic patterns of Influenza in Portugal

The National Influenza Reference Laboratory has been collecting data on influenza activity in Portugal since 1957 through the National Influenza Surveillance Programme, including information on clinical and virological characteristics of the disease, allowing the estimation of weekly incidence rates for influenza-like illness (ILI). This information has not only been used by the National Health Authorities for ...

Pandemic Influenza Virus Surveillance in Portugal: The Laboratory Network for t...

In April 2009 a new influenza A(H1N1) virus of swine origin disseminated throughout the world, resulting in the first pandemic of the XXI century. To face the increasing number of diagnosis being requested, a National Laboratory Network for Influenza Surveillance of the new influenza A(H1N1)pandemic virus was activated in Portugal. This is a descriptive study of the Influenza-like Ilness (ILI) cases reported by...

Heterogeneous Selective Pressure Acting on Influenza B Victoria- and Yamagata-L...

As a consequence of immune pressure, influenza virus hemagglutinin presents some of its amino acids under positive selection. Several authors have reported the existence of influenza A hemagglutinin codons under positive selective pressure (PSP). In this framework, the present work objectives were to demonstrate the presence of PSP and evaluate its effects on Victoria- and Yamagata-like influenza B viruses. Met...

Characterization of influenza A/Fujian/411/2002(H3N2)-like viruses isolated in ...

In Portugal, influenza surveillance is achieved through the National Influenza Surveillance Programme (NISP), in close collaboration with other European and global surveillance networks. The NISP integrates epidemiological, clinical and virological data based on the information collected by a Network of Sentinel Medical Practitioners and by a network of Emergency Units of Hospitals and Health Care Centres. In t...