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Tumor-Infiltrating T Cells in Skin Basal Cell Carcinomas and Squamous Cell Carc...

Cunha, D; Neves, M; Silva, D; Silvestre, AR; Nunes, PB; Arrobas, F; Ribot, JC; Ferreira, F; Moita, LF; Soares-de-Almeida, L; Silva, JM; Filipe, P

Basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) are high-incidence, non-melanoma skin cancers (NMSCs). The success of immune-targeted therapies in advanced NMSCs led us to anticipate that NMSCs harbored significant populations of tumor-infiltrating lymphocytes with potential anti-tumor activity. The main aim of this study was to characterize T cells infiltrating NMSCs. Flow cytometry and immuno...

Date: 2024   |   Origin: Saúde - CUF

Budget impact analysis of cervical cancer screening in Portugal: comparison of ...

Pista, A; Costa, C; Saldanha, C; Moutinho, JA; Moutinho, JM; Arrobas, F; Catalão, C; Kempers, J

BACKGROUND: Primary Human Papilloma Virus (HPV) testing is the currently recommended cervical cancer (CxCa) screening strategy by the Portuguese Society of Gynecology (SPG) clinical consensus. However, primary HPV testing has not yet been adopted by the Portuguese organized screening programs. This modelling study compares clinical benefits and costs of replacing the current practice, namely cytology with ASCUS...

Date: 2019   |   Origin: Saúde - CUF

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