10 documents found, page 1 of 1

Atividade antimicrobiana e antibiofilme de extratos hexânicos de croton blanche...

Os vegetais são conhecidos por produzir grande variedade de compostos ativos que atualmente têm se tornando importantes na busca de novos fármacos. De fato, extratos vegetais tem demonstrado efeito antimicrobiano, atuando sobre formas planctônicas e inibindo a formação de biofilmes. Diante do exposto, o objetivo deste trabalho foi avaliar o efeito antimicrobiano e antibiofilme de extratos hexânicos de diferente...

Potencial biotecnológico de lectinas: indução de apoptose em células A549, efei...

This work evaluated the biotechnological potential of lectins in the induction of apoptosis of neoplastic cells; the effect on wound healing in a murine model (in vivo) and established the level of toxicity on Artemia sp. Lectins are proteins or glycoproteins ubiquitously distributed in nature, being found from bacteria to humans. Since carbohydrates can act as mediators of biological information, the interacti...

Atividade de lectinas de leguminosas sobre a germinação de esporos de fungos fi...

Lectins represent a diversified group of proteins, both in terms of size and structure, as well as in relation to biological activities that they play on different organisms. Most of lectins have been isolated from plants and some of them can exert remarkable antifungal activities. This work shows the effect of five structurally related lectins, which were purified from the seeds of Canavalia ensiformis (ConA),...

Effect of algae and plant lectins on planktonic growth and biofilm formation in...

This study aimed to evaluate the abilities of plant and algae lectins to inhibit planktonic growth and biofilm formation in bacteria and yeasts. Initially, ten lectins were tested on Staphylococcus epidermidis, Staphylococcus aureus, Klebsiella oxytoca, Pseudomonas aeruginosa, Candida albicans, and C. tropicalis at concentrations of 31.25 to 250 μg/mL. The lectins from Cratylia floribunda (CFL), Vatairea macroc...

Antibacterial and antioxidant activities of Derriobtusone A isolated from Lonch...

This study evaluated the effect of derriobtusone A, a flavonoid isolated from Lonchocarpus obtusus, on two important pathogenic bacteria, Staphylococcus aureus and Escherichia coli, as well as its antioxidant activity and toxicity. Planktonic growth assays were performed, and the inhibition of biofilm formation was evaluated. In addition, antioxidant activity was assessed by DPPH radical scavenging assay, ferro...

Effect of a casbane diterpene isolated from Croton nepetaefolius on the prevent...

This study aimed to evaluate the effect of the compound 1,4-dihydroxy-2E,6E,12E-trien-5-one-casbane (CD1CN), a casbane diterpene isolated from Croton nepetaefolius stalks, on the biofilm formation or preformed biofilms of bacteria and yeasts. Minimum inhibitory concentration results showed that CD1CN inhibited the growth of single cultures of Staphylococcus aureus and Candida albicans at 125 and 500 g/mL, respe...

Casbane diterpene activity on mixed biofilms of P. aeruginosa and Candida species

Effect of algae and plant lectins against bacterial biofilm formation

Casbane diterpene as a promising natural antimicrobial agent against biofilm-as...

Croton nepetaefolius is a native plant from northeastern Brazil that belongs to the Euphorbiaceae family. The biological action of this plant has been extensively explored, being the secondary metabolites responsible for its properties alkaloids, diterpenes, and triterpenes. This study aimed to evaluate the ability of casbane diterpene (CD), isolated from the ethanolic extract of C. nepetaefolius, to inhibit mi...

Casbane diterpene as novel and natural antimicrobial agent against biofilm infe...

Croton nepetaefolius is a plant native from northeastern Brazil and belongs to Euphorbiaceae family. The essential oil of this plant is widely used in folk medicine from the treatment of gastrointestinal disorders to the use as an antiseptic agent, with an antifungal action scientifically proven. The action of this plant has been extensively explored by the scientific community, being the secondary metabolites,...