Abstract: We report a complete set of strategies for characterization and an accurate determination of gold in metallic nanoparticles. For this, gold nanorods (AuNR) were synthesized by using the surfactant hexadecyltrimethylammonium bromide (CTAB) as the stabilizer and shape-directing agent. The surfactant CTAB forms a bilayer structure around the nanoparticles and became a challenge for the development of the...
Abstract: Selenium (Se) is an essential micronutrient for humans. Garlic (Allium sativum L.) metabolises Se into important Se-amino acids like Se-methylselenocysteine (Se-MetSeCys), precursor of methylselenol, an active species for cancer prevention. Therefore, the Se accumulation and speciation in garlic were studied to evaluate their relations with growth stages and types of plant clones. Four garlic clones (...
Abstract: As spectral imaging is gaining special attention in the last years, once it allows transforming the chemical information from a sample surface into a high-resolution image of elemental and/or molecular spatial distribution. Then, this review aims to describe fundamental aspects of the main techniques applied to molecular and elemental imaging, such as mass spectrometry (MALDI-MS, DESI-MS, SIMS, and LA...
Agradecimentos: The authors (IS and MAZA) thank the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP, São Paulo, Brazil) (2018/25207-0), and the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Brasília, Brazil) (401170/2016-0) for financial support and fellowships. Additionally, the author MM acknowledges financial support from the Spanish Ministry of Science, Innovation and Uni...
Abstract: The distribution of trace elements in tree rings although poorly known may be useful to better understand environmental changes, pollution trends, long-term droughts, forest dieback processes, and biology of trees. Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is used for imaging micronutrients and potentially toxic elements distribution, allowing the investigation of trace e...
Acompanhado de errata; Abstract: Imbalances in metal concentrations have been suggested to contribute to the pathophysiology of different brain disorders, such as bipolar disorder (BD) and schizophrenia (SCZ). Objectives: The aim of this exploratory study is to evaluate the association between the concentrations of macro/trace elements in serum from BD and SCZ patients considering the effects from different tre...
Abstract: Element constitution and distribution in tissues and body fluids have increasingly become key pieces of information in life sciences and medicine, and trace elements may be successfully used as disease biomarkers. Here, we review the most recent advances in inductively coupled plasma mass spectrometry (ICP-MS) and the related state-of-the-art instrumentation and methods (e.g. single-particle and singl...
Abstract: The widespread application of nanoparticles (NPs) in recent times has caused concern because of their effects in biological systems. Although NPs can be produced naturally, industrially synthesized NPs affect the metabolism of a given organism because of their high reactivity. The biotransformation of NPs involves different processes, including aggregation/agglomeration, and reactions with biomolecule...
Abstract: Understanding the biological process involving metals and biomolecules in the brain is essential for establishing the origin of neurological disorders, such as neurodegenerative and psychiatric diseases. From this perspective, this critical review presents recent advances in this topic, showing possible mechanisms involving the disruption of metal homeostasis and the pathogenesis of neurological disor...
Agradecimentos: The authors (AMA and MAZA) thank the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP, São Paulo, Brazil, 2018/25207-0), the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Brasília, Brazil, 401170/2016-0) and the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, Brasília, Brazil, 88887.115406/2015) for financial support and fellowships. Additio...