32 documents found, page 1 of 4

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Nosocomial lower respiratory tract infections in patients with immunosuppression

Reyes, Luis Felipe; Sanabria-Herrera, Natalia; Nseir, Saad; Ranzani, Otavio T.; Povoa, Pedro; Diaz, Emilio; Schultz, Marcus J.; Rodríguez, Alejandro

Funding Information: This work was supported by the IReL Consortium. European Respiratory Society Clinical Research Collaboration (Prof. Ignacio Martin-Loeches) for The European Network for ICU-Related Respiratory Infections (ENIRRIs), Universidad de La Sabana, Chia, Colombia [Grant Number: MED-244-2018]\u00A0and Clinica Universidad de La Sabana, Chia, Colombia. Publisher Copyright: © The Author(s) 2025.; Backg...


Factors Associated with Mortality in Nosocomial Lower Respiratory Tract Infections

Reyes, Luis Felipe; Torres, Antoni; Olivella-Gomez, Juan; Ibáñez-Prada, Elsa D.; Nseir, Saad; Ranzani, Otavio T.; Povoa, Pedro; Diaz, Emilio

Funding Information: This research was funded by the IReL Consortium. European Respiratory Society Clinical Research Collaboration (Prof Ignacio Martin-Loeches) for The European Network for ICU-Related Respiratory Infections (ENIRRIs) and Universidad de La Sabana [MED-244-2018]. Publisher Copyright: © 2025 by the authors.; Background: Nosocomial lower respiratory tract infections (nLRTIs) are associated with un...


Early bacterial co-infections and ventilator-associated lower respiratory tract...

Rouze, Anahita; Povoa, Pedro; Martin-Loeches, Ignacio; Saura, Ouriel; Maizel, Julien; Pouly, Olivier; Makris, Demosthenes; Du Cheyron, Damien

Funding Information: This study was supported in part by a grant from the French government through the\u2009\u226A\u2009Programme Investissement d\u2019Avenir\u2009\u226B\u2009(I-SITE ULNE) managed by the Agence Nationale de la Recherche (coVAPid project). The funders of the study had no role in the study design, data collection, analysis, or interpretation, writing of the report, or decision to submit for pub...


The association of premorbid conditions with 6-month mortality in acutely admit...

de Lange, Dylan W; Soliman, Ivo W; Leaver, Susannah; Boumendil, Ariane; Haas, Lenneke E M; Watson, Ximena; Boulanger, Carol; Szczeklik, Wojciech

© 2024. The Author(s).; BACKGROUND: Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on 6 month survival. METHODS: Prospective cohort study in 242 ICUs from 22 countries including patients 80 years or above, admitted over a 6 months period to an ICU betwee...


In reply

Wolff, Georg; Wernly, Bernhard; Flaatten, Hans; Fjølner, Jesper; Bruno, Raphael Romano; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.


Evaluation of the Kinetics of Pancreatic Stone Protein as a Predictor of Ventil...

Ceccato, Adrian; Camprubí-Rimblas, Marta; Bos, Lieuwe D.J.; Povoa, Pedro; Martin-Loeches, Ignacio; Forné, Carles; Areny-Balagueró, Aina

Funding Information: This study was partially supported by Abionic, CIBERES, and Research and Innovation Institute Parc Tauli (I3PT). A.C. acknowledges receiving financial support from Instituto de Salud Carlos III (ISCIII; Sara Borrell 2021: CD21/00087). The funding sources had no role in the design and conduct of the study; the collection, management, analysis, and interpretation of the data; the preparation,...


Outcomes of patients aged ≥80 years with respiratory failure initially treated ...

Polok, Kamil; Fronczek, Jakub; Guidet, Bertrand; Artigas, Antonio; De Lange, Dylan W.; Fjølner, Jesper; Leaver, Susannah; Beil, Michael; Sviri, Sigal

Background: Non-invasive ventilation (NIV) has been commonly used to treat acute respiratory failure due to COVID-19. In this study we aimed to compare outcomes of older critically ill patients treated with NIV before and during the COVID-19 pandemic. Methods: We analysed a merged cohort of older adults admitted to intensive care units (ICUs) due to respiratory failure. Patients were enrolled into one of two pr...


Consent is a confounding factor in a prospective observational study of critica...

Flaatten, Hans; Guidet, Bertrand; Jung, Christian; Boumendil, Ariane; Leaver, Susannah; Szczeklik, Wojciech; Artigas, Antonio; Andersen, Finn

During analysis of a prospective multinational observation study of critically ill patients ≥80 years of age, the VIP2 study, we also studied the effects of differences in country consent for study inclusion. This is a post hoc analysis where the ICUs were analyzed according to requirement for study consent. Group A: ICUs in countries with no requirement for consent at admission but with deferred consent in sur...


Noninvasive ventilation in COVID-19 patients aged ≥ 70 years—a prospective mult...

Polok, Kamil; Fronczek, Jakub; Artigas, Antonio; Flaatten, Hans; Guidet, Bertrand; De Lange, Dylan W.; Fjølner, Jesper; Leaver, Susannah; Beil, Michael

Funding Information: COVIP study did not have any funding. Publication of this article was funded by the Priority Research Area qLife under the program “Excellence Initiative – Research University” at the Jagiellonian University in Krakow (06/IDUB/2019/94). Publisher Copyright: © 2022, The Author(s).; Background: Noninvasive ventilation (NIV) is a promising alternative to invasive mechanical ventilation (IMV) w...


Composition and diversity analysis of the lung microbiome in patients with susp...

Fenn, Dominic; Abdel-Aziz, Mahmoud I.; van Oort, Pouline M.P.; Brinkman, Paul; Ahmed, Waqar M.; Felton, Timothy; Artigas, Antonio; Povoa, Pedro

Funding The project was funded by the European Union FP7 Marie Curie Actions, under the Industry-Academia Partnerships and Pathways (IAPP) programme (MC-IAPP BreathDx 611951). WA, TF, PD and SJF were supported by the NIHR Manchester Biochemical Research Centre.; BACKGROUND: Ventilator-associated pneumonia (VAP) is associated with high morbidity and health care costs, yet diagnosis remains a challenge. Analysis ...


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