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In Vitro, Ex Vivo, and In Vivo Evaluation of Silver Nanoparticles Synthesized U...
Cunha, Daniela; Faria-Silva, Catarina; Carvalho, Filomena A.; Ascensão, Lia; Simões, Pedro; Carvalheiro, Manuela; Simões, SandraPublisher Copyright: © 2024 by the authors.; Biogenic silver nanoparticles (AgNP) are among the fastest-growing nanomaterials due to the simplicity, efficiency, and sustainability of their biosynthesis using phytochemicals as reducing and coating agents. The agro-food industry generates large quantities of organic waste, a renewable source of biomolecules for AgNP biosynthesis. The main objective of this work w...
Safety of Gold Nanoparticles
Lopes, Joana; Ferreira-Gonçalves, Tânia; Ascensão, Lia; Viana, Ana S.; Carvalho, Lina; Catarino, José; Faísca, Pedro; Oliva, AbelFunding Information: The authors acknowledge Fundação para a Ciência e a Tecnologia (FCT) for financial support through Projects UIDB/00645/2020, UIDB/04138/2020, UIDP/04138/2020, PTDC/BTM-MAT/31794/2017, and PTDC/QUI-QIN/0586/2020, as well as PhD fellowships SFRH/BD/148044/2019 and SFRH/BD/147306/2019. The authors are also thankful for the financial support to CESAM by FCT/MCTES (UIDP/50017/2020+UIDB/50017/202...
Gold-based nanoplataform for the treatment of anaplastic thyroid carcinoma
Amaral, Mariana; Charmier, Adília J.; Afonso, Ricardo A.; Catarino, José; Faísca, Pedro; Carvalho, Lina; Ascensão, Lia; Coelho, João M.P.Funding: Authors gratefully acknowledge Fundação para a Ciência e a Tecnologia (FCT) through projects UIDB/00645/2020, UIDB/04138/2020, PTDC/MED-QUI/31721/2017, UIDP/04138/2020 and Lusófona University, ULHT. Authors are also thankful to FCT/MCTES for the financial support to CESAM (UIDP/50017/2020, UIDB/50017/2020), through national funds.; Anaplastic thyroid carcinoma (ATC) is a very rare subtype of thyroid ca...
How can biomolecules improve mucoadhesion of oral insulin? A comprehensive insi...
Amaral, Mariana; Martins, Ana Sofia; Catarino, José; Faísca, Pedro; Kumar, Pradeep; Pinto, João F.; Pinto, Rui; Correia, Isabel; Ascensão, LiaFunding: Supported in part by UID/DTP/04138/2019 from FCT, Portugal and DREAMS (ULHT). SEM analysis was funded by FCT/MCTES for the financial support to CESAM (UIDP/50017/2020+UIDB/50017/2020), through national funds.; Currently, insulin can only be administered through the subcutaneous route. Due to the flaws associated with this route, it is of interest to orally deliver this drug. However, insulin delivered ...
Unveiling the mechanism of action of 7α-acetoxy-6β-hydroxyroyleanone on an mrsa...
Pereira, Filipe; Figueiredo, Teresa A.; de Almeida, Rodrigo F. M.; Antunes, Catarina A. C.; Garcia, Catarina; Reis, Catarina P.; Ascensão, LiaUIDB/00100/2020 PTDC/MED-QUI/29036/2017 CEECIND/03414/2018 UIDB/04378/2020 PTDC/BIA-MIC/31645/2017 UID/DTP/04138/2019 UID/DTP/04567/2019 CBIOS/PRUID/BI1/2017 UIDB/04567/2020 UID/AMB/50017 UIDP/50017/2020 UIDB/50017/2020; The number of cases of failure in the treatment of infections associated with resistant bacteria is on the rise, due to the decreasing efficacy of current antibiotics. Notably, 7α-Acetoxy-6β-hy...