13 documents found, page 1 of 2
Genomic monitoring of the SARS-CoV-2 B1.1.7 (WHO VOC Alpha) in the Sao Paulo st...
Slavov, Svetoslav Nanev; Bezerra, Rafael dos Santos; Rodrigues, Evandra Strazza; Santos, Elaine Vieira; Borges, Joseane SerranoMade available in DSpace on 2022-04-28T19:47:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-15; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Financiadora de Estudos e Projetos; The SARS-CoV-2 alpha VOC (also known as lineage B.1.1.7) initially described in the autumn, 2020 in UK, rapidly became the dominant lineage across much of Europe. Despite multiple studies reporting molecul...
SARS-COV-2 genomic monitoring in the state of São Paulo unveils two emerging AY...
Lima, Alex Ranieri Jerônimo; Ribeiro, Gabriela; Viala, Vincent Louis; de Lima, Loyze Paola Oliveira; Martins, Antonio JorgeMade available in DSpace on 2022-04-28T19:51:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; Delta VOC is highly diverse with more than 120 sublineages already described as of November 30, 2021. In this study, through active monitoring of circulating severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants in the state of São Paulo, southeast Brazil, we identified two emerging subl...
Nucleocapsid (N) gene mutations of sars-cov-2 can affect real-time rt-pcr diagn...
Lesbon, Jéssika Cristina Chagas; Poleti, Mirele Daiana; de Mattos Oliveira, Elisângela Chicaroni; Patané, José Salvatore Leister; Clemente, Luan GasparMade available in DSpace on 2022-04-29T08:46:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The current COVID-19 pandemic demands massive testing by Real-time RT-PCR (Reverse Transcription Polym...
In vitro and in vivo effect of peptides derived from 14-3-3 Paracoccidioides sp...
Scorzoni, Liliana [UNESP]; E Silva, Ana Carolina Alves de Paula [UNESP]; de Oliveira, Haroldo Cesar [UNESP]; Dos Santos, Claudia Tavares [UNESP]Made available in DSpace on 2021-06-25T11:10:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Background: Paracoccidioidomycosis (PCM) is a chronic disease that causes sequelae and requires prolonged treatment; therefore, new therapeutic approaches are necessary. I...
Down-regulation of TUFM impairs host cell interaction and virulence by Paracocc...
Marcos, Caroline Maria [UNESP]; Tamer, Gabrielle [UNESP]; de Oliveira, Haroldo Cesar [UNESP]; Assato, Patricia Akemi [UNESP]; Scorzoni, Liliana [UNESP]Made available in DSpace on 2020-12-12T01:46:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The genus Paracoccidioides consist of dimorphic fungi geographically limited to the subtropical regions of Latin America, which are responsible for causing deep systemic mycosis in humans. However, the molecular mechanisms by which Paracocci...
Paracoccidioides brasiliensis 14-3-3 protein is important for virulence in a mu...
Marcos, Caroline Maria [UNESP]; de Oliveira, Haroldo Cesar [UNESP]; Assato, Patricia Akemi [UNESP]; de Andrade, Cleverton Roberto [UNESP]Made available in DSpace on 2019-10-06T16:47:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-10-01; Made available in DSpace on 2019-10-06T16:47:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-10-01; The Paracoccidioides brasiliensis strain downregulated the expression of adhesin Pb14-3-3 (Pb14-3-3 aRNA) was evaluated in a murine model of paracoccidioidomycosis (PCM). Pb14-3-3 aRNA displays ...
Evaluation of Caenorhabditis elegans as a host model for Paracoccidioides brasi...
Scorzoni, Liliana [UNESP]; de Lucas, Maria Pilar; Singulani, Junya de Lacorte [UNESP]; de Oliveira, Haroldo Cesar [UNESP]Made available in DSpace on 2018-12-11T17:18:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-02-01; Paracoccidioidomycosis is a systemic fungal infection affecting mainly Latin American countries that is caused by Paracoccidioides brasiliensis and Paracoccidioides lutzii. During the study of fungal pathogenesis, in vivo studies are crucial to understand the overall mechanisms involving the infection a...
Functional analysis of Paracoccidioides brasiliensis 14-3-3 adhesin expressed i...
Assato, Patricia Akemi [UNESP]; Da Silva, Julhiany De Fátima [UNESP]; De Oliveira, Haroldo Cesar [UNESP]; Marcos, Caroline Maria [UNESP]Made available in DSpace on 2018-12-11T17:26:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-11-04; Made available in DSpace on 2018-12-11T17:26:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-11-04; Background: 14-3-3 proteins comprise a family of eukaryotic multifunctional proteins involved in several cellular processes. The Pb14-3-3 of Paracoccidioides brasiliensis seems to play an import...
Anti-apoptotic effects of decyl gallate on the induction of apoptosis in A549 p...
Bernardi, Thais [UNESP]; De Fátima Da Silva, Julhiany [UNESP]; Vicentin, Juliana [UNESP]; De Oliveira, Haroldo Cesar [UNESP]Made available in DSpace on 2018-12-11T17:15:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-11-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Apoptosis is considered an escapemechanism from the host immune system for the fungus Paracoccidioides spp, and it serves as a vehicle for entry into macrophages wit...
Identification and characterisation of elongation factor Tu, a novel protein in...
Marcos, Caroline Maria [UNESP]; de Oliveira, Haroldo Cesar [UNESP]; da Silva, Julhiany de Fátima [UNESP]; Assato, Patricia Akemi [UNESP]Made available in DSpace on 2018-12-11T17:07:39Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-11-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Paracoccidioides spp., which are temperature-dependent dimorphic fungi, are responsible for the most prevalent human systemic mycosis in Latin America, the paracoccidioidomycosis. The aim of this study was to characterise the involvement of ...