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The natural flavone fukugetin as a mixed-type inhibitor for human tissue kallik...

Santos, Marcelo H. dos; Santos, Jorge A. N.; Kondo, Márcia Y.; Freitas, Renato F.; Ramalho, Teodorico C.; Assis, Diego M.; Juliano, Luiz

The human tissue kallikreins (KLK1–KLK15) comprise a family of 15 serine peptidases detected in almost every tissue of the human body and that actively participate in many physiological and pathological events. Some kallikreins are involved in diseases for which no effective therapy is available, as for example, epithelial disorders, bacterial infections and in certain cancers metastatic processes. In recent ye...

Date: 2018   |   Origin: Oasisbr
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