The genus Croton, belonging to the Euphorbiaceae family, is a plant with shrubby characteristics, with the ability to regrow in times of rain, develops wildly, especially in deforestation areas, being reported mainly in the Caatinga and Forest region. One of the main characteristics of this genus is that several species are rich in chemical constituents of importance for medicine. In this way, this review of th...
Annona muricata (soursop) is a native American plant and is well known for its leafy canopy and its fruits, widely consumed in South America and Southeast Asia. The objective of this work was to obtain Annona muricata leaf extracts and to evaluate their antioxidant activities, which were obtained by four different extraction methods: Soxhlet, maceration, ultrasound, and pressurized hot (subcritical) water. In o...
The purpose of this study was to evaluate the safety of Kalanchoe brasiliensis extract, followed by the development of an oil in water emulsion containing the K. brasiliensis leaves extract and evaluating its clinical moisturizing efficacy. The formulations containing sodium acrylates/ Beheneth-25 methacrylate Crosspolymer (and) hydrogenated polydecene (and) lauryl glucoside and 0.5% of extract were prepared. T...
Submitted by ROBERTO PAULO CORREIA DE ARAÚJO (ppgorgsistem@ufba.br) on 2017-06-05T19:15:05Z No. of bitstreams: 1 9_v.10_2.pdf: 185613 bytes, checksum: 364227f735ffb2fd5ae85e9ef5a69c3f (MD5); Made available in DSpace on 2017-06-05T19:15:05Z (GMT). No. of bitstreams: 1 9_v.10_2.pdf: 185613 bytes, checksum: 364227f735ffb2fd5ae85e9ef5a69c3f (MD5) Previous issue date: 2011-05; Objetivou-se verificar as alterações sa...
The purpose of this study was to determine naproxen concentrations in rat plasma samples by HPLC and to compare the bioavailability of a generic and two compounded naproxen sodium suspensions (test 1 and test 2). Analysis was run at a fl ow rate of 1.2 mL.min-1 with a mobile phase of acetonitrile: NaH2PO4 0.01 M pH 4.00 (50:50, v/v) at 280 nm, using a C18 column (150 mm x 4.6 mm, 5 μm). The calibration curve wa...
Constituiu objetivo deste trabalho o desenvolvimento tecnológico de formas farmacêuticas obtidas a partir de Phyllanthus niruri L. (Euphorbiaceae), incluso no Projeto de Pesquisa de Plantas Medicinais da Central de Medicamentos. Para tanto, foram desenvolvidas metodologias analíticas capazes de avaliar a qualidade da matéria-prima, das ações de transformação, dos produtos intermediários e do produto final. Estu...
As folhas de Maytenus ilicifolia são amplamente utilizadas na medicina tradicional brasileira no tratamento de distúrbios gástricos. Após a comprovação de sua eficácia e segurança, a referida droga vegetal tem sido objeto de diversos estudos com a finalidade de estabelecer parâmetros para o controle de qualidade. Neste sentido, foi avaliada a viabilidade do desenvolvimento de um método analítico fundamentado na...
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The aim of this study was to evaluate the quality of five different solid formulations of carbamazepine. The reference formulation was Tegretol® 200.00 mg (Novartis) and the others were: generic formulation of carbamazepine 200.00 mg (National Industry), similar formulation of carbamazepine 200.00 mg (National Industry), and two formulations of carbamazepine 200.00 mg acquired from two different compounding pha...