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Oxidative damage and response to Bacillus Calmette-Guérin in bladder cancer cel...

Severino, P; Silva, M; Carrascal, M; Malagolini, N; Chiricolo, M; Venturi, G; Barbaro Forleo, R; Astolfi, A; Catera, M; Videira, P; Dall'Olio, F

Treatment with Bacillus Calmette-Guérin (BCG) is the gold standard adjuvant immunotherapy of non-muscle invasive bladder cancer (NMIBC), although it fails in one third of the patients. NMIBC expresses two tumor-associated O-linked carbohydrates: the disaccharide (Galß1,3GalNAc) Thomsen-Friedenreich (T) antigen, and its sialylated counterpart (Siaa2,3Galß1,3GalNAc) sialyl-T (sT), synthesized by sialyltransferase...

Date: 2018   |   Origin: Repositório Aberto da Universidade do Porto
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