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Curcumin Inhibits Gastric Inflammation Induced by Helicobacter Pylori Infection...

Santos, António; Lopes, Teresa; Oleastro, Mónica; Gato, Inês; Floch, Pauline; Benejat, Lucie; Chaves, Paula; Pereira, Teresa; Seixas, Elsa

Helicobacter pylori (H. pylori) infection triggers a sequence of gastric alterations starting with an inflammation of the gastric mucosa that, in some cases, evolves to gastric cancer. Efficient vaccination has not been achieved, thus it is essential to find alternative therapies, particularly in the nutritional field. The current study evaluated whether curcumin could attenuate inflammation of the gastric muco...


Helicobacter pylori infection: the role of intestinal

Machado, Jorge; Gato, Inês; Lopes, Teresa; Pereira, Teresa; Santos, Mário; Oleastro, Mónica; Chaves, Paula; Guerreiro, António

Intestinal microbiota may influence inflammation in the host. The aim of the present study was to explore the role of modulation of intestinal microbiota in the outcome in the Helicobacter pylori (Hp) gastric inflammation. Twenty five C57BL/6 male mice were separated in three groups: Control group (CG) n = 5 Infected group (IG) n = 10 and Synbiotic 2000TM (SG) n = 10. CG received PBS by gavage; IG and SG were i...


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