3 documents found, page 1 of 1
Utility of Gene Panels for the Diagnosis of Inborn Errors of Metabolism in a Me...
Barbosa-Gouveia, S; Vázquez-Mosquera, ME; González-Vioque, E; Álvarez, JV; Chans, R; Laranjeira, F; Martins, E; Ferreira, AC; Avila-Alvarez, ANext-generation sequencing (NGS) technologies have been proposed as a first-line test for the diagnosis of inborn errors of metabolism (IEM), a group of genetically heterogeneous disorders with overlapping or nonspecific phenotypes. Over a 3-year period, we prospectively analyzed 311 pediatric patients with a suspected IEM using four targeted gene panels. The rate of positive diagnosis was 61.86% for intermedia...
Assessment of Continuous Pain in Newborns Admitted to NICUs in 18 European Coun...
Anand, K; Eriksson, M; Boyle, E; Avila-Alvarez, A; Andersen, R; Sarafidis, K; Polkki, T; Matos, C; Lago, P; Papadouri, T; Attard-Montalto, S; Ilmoja, MLAIM: Continuous pain occurs routinely, even after invasive procedures, or inflammation and surgery, but clinical practices associated with assessments of continuous pain remain unknown. METHODS: A prospective cohort study in 243 neonatal intensive care units (NICUs) from 18 European countries recorded the frequency of pain assessments, use of mechanical ventilation, sedation, analgesia or neuromuscular blockade...
Sedation and Analgesia Practices in Neonatal Intensive Care Units (EUROPAIN): R...
Carbajal, R; Eriksson, M; Boyle, E; Avila-Alvarez, A; Dovland Andersen, R; Sarafidis, K; Polkki, T; Matos, C; Lago, P; Papadouri, T; Attard Montalto, SBACKGROUND: Neonates who are in pain or are stressed during care in the intensive care unit (ICU) are often given sedation or analgesia. We investigated the current use of sedation or analgesia in neonatal ICUs (NICUs) in European countries. METHODS: EUROPAIN (EUROpean Pain Audit In Neonates) was a prospective cohort study of the management of sedation and analgesia in patients in NICUs. All neonates admitted t...