Six previously undescribed tropane alkaloids, designated as erythrobezerrines A-F, were isolated from the EtOH extract from the stem bark of Erythroxylum bezerrae Plowman. Their structures were elucidated based on the interpretation of the NMR and MS data and in some instances, confirmed by X-ray diffraction analysis. The cytotoxicity of the isolated compounds was evaluated against the cancer cell lines L929, P...
The use of supramolecular synthons as a strategy to control crystalline structure is a crucial factor in developing new solid forms with physicochemical properties optimized by design. However, to achieve this objective, it is necessary to understand the intermolecular interactions in the context of crystal packing. The feasibility of a given synthon depends on its flexibility to combine the drug with a variety...
Made available in DSpace on 2018-12-11T16:59:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-01-01; Interfacial cross-linking (ICL) has been considered a feasible technique to produce polysaccharide-based microparticles (PbMs), even though only a few studies have been concerned with their biocompatibility. In this work, PbMs were prepared by the ICL method and characterized in regard to their in vitro...
Texto completo: acesso restrito. p. 1601–1605; Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-03-11T13:45:48Z No. of bitstreams: 1 J. S. Boaventura Filho.pdf: 250852 bytes, checksum: 8a3ab38cb69baf1952435853b0ae4cb1 (MD5); Made available in DSpace on 2014-03-11T13:45:48Z (GMT). No. of bitstreams: 1 J. S. Boaventura Filho.pdf: 250852 bytes, checksum: 8a3ab38cb69baf1952435853b0ae4cb1 (MD5) Previous ...
Texto completo: acesso restrito. p. 165-179; Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-10-11T12:08:24Z No. of bitstreams: 1 1-s2.0-S0926860X09001574-main.pdf: 834366 bytes, checksum: ff710893da1fa4171688240f210f8ac8 (MD5); Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-18T21:18:58Z (GMT) No. of bitstreams: 1 1-s2.0-S0926860X09001574-main.pdf: 834366 bytes, ch...
We report Raman scattering and x-ray diffraction studies of polycrystalline CaCu3Ti4O12 (CCTO) under high pressures. The pressure dependence of several Raman modes was investigated. No anomalies have been observed on the phonon spectra thereby indicating that the Th sIm 3¯d structure remains stable up to the maximum pressure s5.3 GPad we reached in this experiment. The pressure coefficients for the observed Ram...