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Neurophysiological correlates of tactile width discrimination in humans

Pais-Vieira, Carla; Allahdad, Mehrab K; Perrotta, André; Peres, André; Kunicki, Carolina; Aguiar, Mafalda; Oliveira, Manuel; Pais-Vieira, Miguel

Introduction: Tactile information processing requires the integration of sensory, motor, and cognitive information. Width discrimination has been extensively studied in rodents, but not in humans. Methods: Here, we describe Electroencephalography (EEG) signals in humans performing a tactile width discrimination task. The first goal of this study was to describe changes in neural activity occurring during the di...


Neurophysiological correlates of tactile width discrimination in humans

Pais-Vieira, Carla; Allahdad, Mehrab K.; Perrotta, André; Peres, André S.; Kunicki, Carolina; Aguiar, Mafalda; Oliveira, Manuel; Pais-Vieira, Miguel

Introduction: Tactile information processing requires the integration of sensory, motor, and cognitive information. Width discrimination has been extensively studied in rodents, but not in humans. Methods: Here, we describe Electroencephalography (EEG) signals in humans performing a tactile width discrimination task. The first goal of this study was to describe changes in neural activity occurring during the di...


Ceftriaxone modulates the acute corticosterone effects in local field potential...

Pais-Vieira, Miguel; Kunicki, Carolina; Peres, André; Sousa, Nuno

Stress responses are associated with elevations in corticosterone levels and, as a consequence, increases in glutamate in the central nervous system which can lead to neurological impairment. Ceftriaxone promotes glutamate transport and has been used to reduce glutamate toxicity, but so far it is not known whether ceftriaxone is able to reverse the effects of corticosterone administration. Here we describe the ...


Frequency-specifc coupling in fronto-parieto-occipital cortical circuits underl...

Kunicki, Carolina; Moioli, Renan C.; Pais-Vieira, Miguel; Peres, André Salles Cunha; Morya, Edgard; Nicolelis, Miguel A. L.

Processing of tactile sensory information in rodents is critically dependent on the communication between the primary somatosensory cortex (S1) and higher-order integrative cortical areas. Here, we have simultaneously characterized single-unit activity and local field potential (LFP) dynamics in the S1, primary visual cortex (V1), anterior cingulate cortex (ACC), posterior parietal cortex (PPC), while freely mo...


Frequency-specific coupling in fronto-parieto-occipital cortical circuits under...

Kunicki, Carolina; Moioli, Renan C.; Pais-Vieira, Miguel; Peres, André Salles Cunha; Morya, Edgard; Nicolelis, Miguel A. L.

Processing of tactile sensory information in rodents is critically dependent on the communication between the primary somatosensory cortex (S1) and higher-order integrative cortical areas. Here, we have simultaneously characterized single-unit activity and local field potential (LFP) dynamics in the S1, primary visual cortex (V1), anterior cingulate cortex (ACC), posterior parietal cortex (PPC), while freely mo...


Ceftriaxone modulates the acute corticosterone effects in local field potential...

Pais-Vieira, Miguel; Kunicki, Carolina; Peres, André; Sousa, Nuno

Stress responses are associated with elevations in corticosterone levels and, as a consequence, increases in glutamate in the central nervous system which can lead to neurological impairment. Ceftriaxone promotes glutamate transport and has been used to reduce glutamate toxicity, but so far it is not known whether ceftriaxone is able to reverse the effects of corticosterone administration. Here we describe the ...


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