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In vitro selection of DNA aptamers against human osteosarcoma

Tsogtbaatar, Khaliunsarnai; Sousa, Diana Andrade; Ferreira, Débora Carina Gonçalves Abreu; Tevlek, Atakan; Aydin, Halil Murat; Çelik, Eda

Background. Osteosarcoma is a highly malignant bone tumor, most frequently occurring in the rapid bone growth phase. Effective treatment of this disease is hindered by the lack of specific probes for early diagnosis and the fast cancer widespread. Methods. To find such probes, the cell-Systematic Evolution of Ligands by EXponential enrichment (cell-SELEX) methodology was implemented against the human osteosarco...

Date: 2022   |   Origin: RepositóriUM - Universidade do Minho
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