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Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iN...

Paiva, Ricardo S.; Ramos, Camila V.; Azenha, Sara R.; Alves, Carolina; Basto, Afonso; Graca, Luis; Martins, Vera C.

Peptidyl-prolyl cis-trans isomerase C (Ppic) is expressed in several bone marrow (BM) hematopoietic progenitors and in T-cell precursors. Since the expression profile of Ppic in the hematoimmune system was suggestive that it could play a role in hematopoiesis and/or T lymphocyte differentiation, we sought to test that hypothesis in vivo. Specifically, we generated a Ppic-deficient mouse model by targeting the e...


Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iN...

Paiva, Ricardo S.; Ramos, Camila V.; Azenha, Sara R.; Alves, Carolina; Basto, Afonso P.; Graça, Luís; Martins, Vera C.

Peptidyl-prolyl cis-trans isomerase C (Ppic) is expressed in several bone marrow (BM) hematopoietic progenitors and in T-cell precursors. Since the expression profile of Ppic in the hematoimmune system was suggestive that it could play a role in hematopoiesis and/or T lymphocyte differentiation, we sought to test that hypothesis in vivo. Specifically, we generated a Ppic-deficient mouse model by targeting the e...


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