8 documents found, page 1 of 1
Supervised independent component analysis as an alternative method for genomic ...
Azevedo, C.F.; Silva, F.F.; Resende, M.D.V. de; Lopes, M.S.; Duijvesteijn, N.; Guimarães, S.E.F.; Lopes, P.S.; Kelly, M.J.; Viana, J.M.S.; Knol, E.F.The objective of this work was to evaluate the efficiency of the supervised independent component regression (SICR) method for the estimation of genomic values and the SNP marker effects for boar taint and carcass traits in pigs. The methods were evaluated via the agreement between the predicted genetic values and the corrected phenotypes observed by cross-validation. These values were also compared with other ...
Factor analysis applied to genome prediction for high-dimensional phenotypes in...
Teixeira, F.R.F.; Nascimento, M.; Nascimento, A.C.C.; Silva, F.F. e; Cruz, C.D.; Azevedo, C.F.; Paixão, D.M.; Barroso, L.M.A.; Verardo, L.L.The aim of the present study was to propose and evaluate the use of factor analysis (FA) in obtaining latent variables (factors) that represent a set of pig traits simultaneously, for use in genomewide selection (GWS) studies. We used crosses between outbred F2 populations of Brazilian Piau X commercial pigs. Data were obtained on 345 F2 pigs, genotyped for 237 SNPs, with 41 traits. FA allowed us to obtain four...
Genomic prediction for additive and dominance effects of censored traits in pigs
Santos, V.S.; Martins Filho, S.; Resende, M.D.V.; Azevedo, C.F.; Lopes, P.S.; Guimarães, S.E.F.; Silva, F.F.Número de páginas não informado.; Age at the time of slaughter is a commonly used trait in animal breeding programs. Since studying this trait involves incomplete observations (censoring), analysis can be performed using survival models or modified linear models, for example, by sampling censored data from truncated normal distributions. For genomic selection, the greatest genetic gains can be achieved by inclu...
New accuracy estimators for genomic selection with application in a cassava (Ma...
Azevedo, C.F.; Resende, M.D.V.; Silva, F.F.; Viana, J.M.S.; Resende Jr, M.F.R.; Oliveira, E.J.; Valente, M.S.F.Genomic selection is the main force driving applied breeding programs and accuracy is the main measure for evaluating its efficiency. The traditional estimator (TE) of experimental accuracy is not fully adequate. This study proposes and evaluates the performance and efficiency of two new accuracy estimators, called regularized estimator (RE) and hybrid estimator (HE), which were applied to a practical cassava b...
Genome wide selection in Citrus breeding
Gois, I.B.; Borém, A.; Cristofani-Yaly, M.; Resende, M.D.V. de; Azevedo, C.F.; Bastianel, M.; Novelli, V.M.; Machado, M.A.Genome wide selection (GWS) is essential for the genetic improvement of perennial species such as Citrus because of its ability to increase gain per unit time and to enable the efficient selection of characteristics with low heritability. This study assessed GWS efficiency in a population of Citrus and compared it with selection based on phenotypic data. A total of 180 individual trees from a cross between Pera...
Estimating additive and dominance variances for complex traits in pigs combinin...
Costa, E.V.; Diniz, D.B.; Veroneze, R.; Resende, M.D.V.; Azevedo, C.F.; Guimaraes, S.E.F.; Silva, F.F.; Lopes, P.S.Knowledge of dominance effects should improve ge-netic evaluations, provide the accurate selection of purebred animals, and enable better breeding strategies, including the exploitation of het-erosis in crossbreeds. In this study, we combined genomic and pedi-gree data to study the relative importance of additive and dominance genetic variation in growth and carcass traits in an F2 pig population. Two GBLUP mod...
Genomic selection for slaughter age in pigs using the Cox frailty model
Santos, V.S.; Martins Filho, S.; Resende, M.D.V.; Azevedo, C.F.; Lopes, P.S.; Guimarães, S.E.F.; Glória, L.S.; Silva, F.F.The aim of this study was to compare genomic selection methodologies using a linear mixed model and the Cox survival model. We used data from an F2 population of pigs, in which the response variable was the time in days from birth to the culling of the animal and the covariates were 238 markers [237 single nucleotide polymorphism (SNP) plus the halothane gene]. The data were corrected for fixed effects, and the...
Comparison of dimensionality reduction methods to predict genomic breeding valu...
Azevedo, C.F.; Nascimento, M.; Silva, F.F.; Resende, M.D.V.; Lopes, P.S.; Guimarães, S.E.F.; Glória, L.S.A significant contribution of molecular genetics is the direct use of DNA information to identify genetically superior individuals. With this approach, genome-wide selection (GWS) can be used for this purpose. GWS consists of analyzing a large number of single nucleotide polymorphism markers widely distributed in the genome; however, because the number of markers is much larger than the number of genotyped indi...