8 documents found, page 1 of 1
Proposal of a lightweight, offline, full-text search engine for an mHealth app
Carla Teixeira Lopes; Azevedo, D; Monteiro, JM- A patient's ability to recall and retrieve health information contributes to a better health management. HealthTalks was developed to address these issues by recording a summary of a medical appointment, uttered by the physician, and transcribing it. For each appointment, the user can also take free-text notes. Nowadays, search engines have become a ubiquitous part of everyone's life and are expected on most ...
Prognostic significance of MUC2, CDX2 and SOX2 in stage II colorectal cancer pa...
Ribeirinho-Soares, S; Pádua, D; Amaral, AL; Valentini, E; Azevedo, D; Marques, C; Barros, R; Macedo, F; Mesquita, P; Almeida, RBackground: Colorectal cancer (CRC) remains a serious health concern worldwide. Despite advances in diagnosis and treatment, about 15 to 30% of stage II CRC patients subjected to tumor resection with curative intent, develop disease relapse. Moreover, the therapeutic strategy adopted after surgery is not consensual for these patients. This supports the imperative need to find new prognostic and predictive bioma...
Antiangiogenic and antioxidant in vitro properties of hydroethanolic extract fr...
Costa, R; Azevedo, D; Barata, P; Soares, R; Guido, LF; Carvalho, DOThe Euterpe oleracea fruit (açaí) is a promising source of polyphenols with health-promoting properties. To our knowledge, few studies have focused on the influence of açaí phytochemicals on angiogenesis, with a significant impact on cancer. This study aimed at investigating the phytochemical profile of a purple açaí hydroethanolic extract (AHE) obtained from a commercial dietary powder supplement by high-perfo...
Meta-Analysis of Relation of Epicardial Adipose Tissue Volume to Left Atrial Di...
Mancio, J; Azevedo, D; Fragão-Marques, M; Falcão-Pires, I; Leite-Moreira, A; Lunet, N; Fontes-Carvalho, R; Bettencourt, NMany studies have explored the hypothesis that epicardial adipose tissue (EAT) accumulation adversely affects cardiac remodeling. We assessed, through a systematic review and meta-analysis, whether EAT is linked to left atrial (LA) and left ventricular (LV) structure and function, irrespective of global or abdominal visceral adiposity. We searched MEDLINE, Scopus, and Web of Science for studies evaluating the a...
Expression and clinical relevance of SOX9 in gastric cancer
Mesquita, P; Freire, AF; Lopes, N; Gomes, R; Azevedo, D; Barros, R; Pereira, B; Cavadas, B; Pópulo, H; Boaventura, P; David, L; Pereira, L; Almeida, RGastric cancer is one of the most frequent tumours and the third leading cause of cancer-related death worldwide. The investigation of new biomarkers that can predict patient outcome more accurately and allow better treatment and follow-up decisions is of crucial importance. SOX9 (sex-determining region Y (SRY)-box 9) is a regulator of cell fate decisions in embryogenesis and adulthood. Here, we sought to ascer...
Epicardial adipose tissue volume assessed by computed tomography and coronary a...
Mancio, J; Azevedo, D; Saraiva, F; Azevedo, A; Pires-Morais, G; Leite-Moreira, A; Falcao-Pires, I; Lunet, N; Bettencourt, NTo conduct a systematic review and meta-analysis on the crude and adjusted associations between epicardial adipose tissue (EAT) volume determined by computed tomography (CT) and coronary artery disease (CAD). MEDLINE, Scopus, and Web of Science databases were screened for all observational studies assessing the association between EAT volume and CAD. We calculated pooled odds ratio (OR) or hazard ratio (HR) and...
Extreme Value Laws for Dynamical Systems with Countable Extremal Sets
Azevedo, D; Ana Cristina Moreira Freitas; Jorge Milhazes Freitas; Rodrigues, FBWe consider stationary stochastic processes arising from dynamical systems by evaluating a given observable along the orbits of the system. We focus on the extremal behaviour of the process, which is related to the entrance in certain regions of the phase space, which correspond to neighbourhoods of the maximal set (Formula presented.), i.e.,the set of points where the observable is maximised. The main novelty ...
Clustering of extreme events created by multiple correlated maxima
Azevedo, D; Ana Cristina Moreira Freitas; Jorge Milhazes Freitas; Rodrigues, FBWe consider stochastic processes arising from dynamical systems by evaluating an observable function along the orbits of the system. The novelty is that we will consider observables achieving a global maximum value (possible infinite) at multiple points with special emphasis for the case where these maximal points are correlated or bound by belonging to the same orbit of a certain chosen point. These multiple c...